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Xpovio and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is reported as a side effect among people who take Xpovio (selinexor), especially for people who are have been taking the drug for < 1 month also take Pomalyst, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Joint swelling when taking Xpovio. It is created by eHealthMe based on reports of 5,192 people who have side effects when taking Xpovio from the FDA, and is updated regularly.

What is Xpovio?

Xpovio has active ingredients of selinexor. eHealthMe is studying from 5,193 Xpovio users. Check the latest studies of Xpovio.

What is Joint swelling?

Joint swelling is found to be associated with 2,122 drugs and 2,935 conditions by eHealthMe. Check the latest studies of Joint swelling.

On Jul, 14, 2026

5,192 people reported to have side effects when taking Xpovio.
Among them, 28 people (0.54%) have Joint swelling.

Could Xpovio cause Joint swelling?

Among these 28 people:

How long have people been on Xpovio when they have Joint swelling? *

  • < 1 month: 58.33 %
  • 1 - 6 months: 33.33 %
  • 6 - 12 months: 8.33 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What are other drugs people take besides Xpovio? *

  1. Pomalyst: 10 people, 35.71%
  2. Ondansetron: 8 people, 28.57%
  3. Dexamethasone: 8 people, 28.57%
  4. Drisdol: 5 people, 17.86%
  5. Lomotil: 4 people, 14.29%
  6. Colace: 4 people, 14.29%
  7. Empliciti: 4 people, 14.29%
  8. Famotidine: 4 people, 14.29%
  9. Furosemide: 4 people, 14.29%
  10. Gabapentin: 4 people, 14.29%

What are other side effects people have besides Joint swelling? *

  1. Fatigue (feeling of tiredness): 17 people, 60.71%
  2. Diarrhea: 12 people, 42.86%
  3. Nausea (feeling of having an urge to vomit): 10 people, 35.71%
  4. Constipation: 9 people, 32.14%
  5. Weakness: 9 people, 32.14%
  6. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 9 people, 32.14%
  7. Peripheral Swelling: 9 people, 32.14%
  8. Dyspnea (difficult or laboured breathing): 6 people, 21.43%
  9. Thrombocytopenia (decrease of platelets in blood): 6 people, 21.43%
  10. White Blood Cell Count Decreased: 5 people, 17.86%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 27 people, 96.43%
  2. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 3.57%
  3. Hyperglycemia (high blood sugar): 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Xpovio and have Joint swelling?

- Check whether Joint swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xpovio:

Joint swelling treatments and more:

How severe was Joint swelling and when was it recovered:

Expand to all the drugs that have ingredients of selinexor:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xpovio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint swelling:

Browse all the conditions that are associated with Joint swelling:

How the study uses the data?

The study uses data from the FDA. It is based on selinexor (the active ingredients of Xpovio) and Xpovio (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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