Xylocaine and Hyperglycemia - a phase IV clinical study of FDA data

Summary:

Hyperglycemia is reported as a side effect among people who take Xylocaine (lidocaine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Hyperglycemia when taking Xylocaine. It is created by eHealthMe based on reports of 5,700 people who have side effects when taking Xylocaine from the FDA, and is updated regularly.

What is Xylocaine?

Xylocaine has active ingredients of lidocaine hydrochloride. eHealthMe is studying from 5,716 Xylocaine users. Check the latest studies of Xylocaine.

What is Hyperglycemia?

Hyperglycemia (high blood sugar) is found to be associated with 1,658 drugs and 2,501 conditions by eHealthMe. Check the latest studies of Hyperglycemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

5,700 people reported to have side effects when taking Xylocaine.
Among them, 21 people (0.37%) have Hyperglycemia.

Among these 21 people:

How long have people been on Xylocaine when they have Hyperglycemia? *

What is the gender of people who have Hyperglycemia when taking Xylocaine? *

female: 52.63 %
male: 47.37 %

What is the age of people who have Hyperglycemia when taking Xylocaine? *

What are other drugs people take besides Xylocaine? *

What are other side effects people have besides Hyperglycemia? *

Stress And Anxiety: 9 people, 42.86%
Headache (pain in head): 8 people, 38.10%
Confusional State: 7 people, 33.33%
Pain: 7 people, 33.33%
Febrile Neutropenia (fever with reduced white blood cells): 7 people, 33.33%
Dizziness: 7 people, 33.33%
Nausea (feeling of having an urge to vomit): 6 people, 28.57%
Impaired Healing: 6 people, 28.57%
Nausea And Vomiting: 6 people, 28.57%
Osteomyelitis (infection of bone): 6 people, 28.57%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 4 people, 19.05%
Immunodeficiency Disorders: 3 people, 14.29%
Headache (pain in head): 2 people, 9.52%
High Blood Cholesterol: 2 people, 9.52%
Bipolar Disorder (mood disorder): 2 people, 9.52%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 9.52%
Irritable Bowel Syndrome: 2 people, 9.52%
Intestinal Functional Disorder: 2 people, 9.52%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 4.76%
Gastric Ulcer (stomach ulcer): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Xylocaine and have Hyperglycemia?

- Check whether Hyperglycemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xylocaine:

Xylocaine (5,716 reports)

Hyperglycemia treatments and more:

Hyperglycemia (48,691 reports)

Browse all side effects of Xylocaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperglycemia:

Hyperglycemia (1,658 drugs)

Browse all the conditions that are associated with Hyperglycemia:

Hyperglycemia (2,501 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lidocaine hydrochloride (the active ingredients of Xylocaine) and Xylocaine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.