Xyzal and Nephropathy - a phase IV clinical study of FDA data

Summary:

Nephropathy is reported as a side effect among people who take Xyzal (levocetirizine dihydrochloride), especially for people who are male, 50-59 old, have been taking the drug for 1 - 2 years also take Prevacid, and have High blood pressure.

The phase IV clinical study analyzes which people have Nephropathy when taking Xyzal. It is created by eHealthMe based on reports of 20,548 people who have side effects when taking Xyzal from the FDA, and is updated regularly.

What is Xyzal?

Xyzal has active ingredients of levocetirizine dihydrochloride. It is often used in allergies. eHealthMe is studying from 21,479 Xyzal users. Check the latest studies of Xyzal.

What is Nephropathy?

Nephropathy (damage to or disease of a kidney) is found to be associated with 901 drugs and 733 conditions by eHealthMe. Check the latest studies of Nephropathy.

On Jul, 12, 2026

20,548 people reported to have side effects when taking Xyzal.
Among them, 13 people (0.06%) have Nephropathy.

Among these 13 people:

How long have people been on Xyzal when they have Nephropathy? *

What is the gender of people who have Nephropathy when taking Xyzal? *

female: 38.46 %
male: 61.54 %

What is the age of people who have Nephropathy when taking Xyzal? *

What are other drugs people take besides Xyzal? *

What are other side effects people have besides Nephropathy? *

Chronic Kidney Disease: 8 people, 61.54%
Acute Kidney Failure: 8 people, 61.54%
Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 5 people, 38.46%
Rickets (softening of bones): 4 people, 30.77%
Prostatomegaly (enlargement of the prostate): 4 people, 30.77%
Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 4 people, 30.77%
Renal Injury (kidney injury): 3 people, 23.08%
Interstitial Nephritis (inflammation of the kidney): 2 people, 15.38%
Renal Impairment (severely reduced kidney function): 1 person, 7.69%
Nephrogenic Anaemia (anaemia due to kidney disease): 1 person, 7.69%

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 61.54%
High Blood Pressure: 8 people, 61.54%
Hypersensitivity: 6 people, 46.15%
Gout (uric acid crystals building up in the body): 4 people, 30.77%
Pain: 4 people, 30.77%
Stress And Anxiety: 4 people, 30.77%
Depression: 4 people, 30.77%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 30.77%
Itching: 3 people, 23.08%
Vitamin D Decreased: 3 people, 23.08%

* Approximation only. Some reports may have incomplete information.

Do you take Xyzal and have Nephropathy?

- Check whether Nephropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xyzal:

Xyzal (21,479 reports)

Nephropathy treatments and more:

Nephropathy (16,529 reports)

How severe was Nephropathy and when was it recovered:

Nephropathy in Xyzal

Expand to all the drugs that have ingredients of levocetirizine dihydrochloride:

Nephropathy and drugs with ingredients of levocetirizine dihydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xyzal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nephropathy:

Nephropathy (901 drugs)

Browse all the conditions that are associated with Nephropathy:

Nephropathy (733 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on levocetirizine dihydrochloride (the active ingredients of Xyzal) and Xyzal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.