Yaz and Rash macular - a phase IV clinical study of FDA data

Summary:

Rash macular is reported as a side effect among people who take Yaz (drospirenone; ethinyl estradiol), especially for people who are female, 30-39 old, have been taking the drug for 1 - 2 years also take Naproxen, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Rash macular when taking Yaz. It is created by eHealthMe based on reports of 39,984 people who have side effects when taking Yaz from the FDA, and is updated regularly.

What is Yaz?

Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,514 Yaz users. Check the latest studies of Yaz.

What is Rash macular?

Rash macular (small, flat red spots) is found to be associated with 1,365 drugs and 1,512 conditions by eHealthMe. Check the latest studies of Rash macular.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

39,984 people reported to have side effects when taking Yaz.
Among them, 17 people (0.04%) have Rash macular.

Among these 17 people:

How long have people been on Yaz when they have Rash macular? *

What is the gender of people who have Rash macular when taking Yaz? *

female: 100 %
male: 0.0 %

What is the age of people who have Rash macular when taking Yaz? *

What are other drugs people take besides Yaz? *

Naproxen: 4 people, 23.53%
Lidocaine: 3 people, 17.65%
Ondansetron: 3 people, 17.65%
Albuterol: 3 people, 17.65%
Calcium: 3 people, 17.65%
Clonazepam: 3 people, 17.65%
Epinephrine: 3 people, 17.65%
Fexofenadine Hydrochloride: 3 people, 17.65%
Fish Oil: 3 people, 17.65%
Hizentra: 3 people, 17.65%

What are other side effects people have besides Rash macular? *

Itching: 7 people, 41.18%
Rashes (redness): 5 people, 29.41%
Abdominal Discomfort: 4 people, 23.53%
Fever: 4 people, 23.53%
Nausea (feeling of having an urge to vomit): 4 people, 23.53%
Pain: 4 people, 23.53%
Headache (pain in head): 3 people, 17.65%
Post Procedural Complication: 3 people, 17.65%
Kidney Stones: 3 people, 17.65%
Yellow Skin: 2 people, 11.76%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 3 people, 17.65%
Migraine (headache): 2 people, 11.76%
Skin Wrinkling (wrinkle on skin): 2 people, 11.76%
Depression: 2 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.76%
Pain: 2 people, 11.76%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.88%
Dry Skin: 1 person, 5.88%
Headache (pain in head): 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Yaz and have Rash macular?

- Check whether Rash macular is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Yaz:

Yaz (41,514 reports)

Rash macular treatments and more:

Rash macular (36,440 reports)

How severe was Rash macular and when was it recovered:

Rash macular in Yaz

Expand to all the drugs that have ingredients of drospirenone; ethinyl estradiol:

Rash macular and drugs with ingredients of drospirenone; ethinyl estradiol

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Yaz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rash macular:

Rash macular (1,365 drugs)

Browse all the conditions that are associated with Rash macular:

Rash macular (1,512 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on drospirenone; ethinyl estradiol (the active ingredients of Yaz) and Yaz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.