Yaz and Tibia fracture - a phase IV clinical study of FDA data

Summary:

Tibia fracture is reported as a side effect among people who take Yaz (drospirenone; ethinyl estradiol), especially for people who are female, 20-29 old, have been taking the drug for 1 - 6 months also take Zoloft, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Tibia fracture when taking Yaz. It is created by eHealthMe based on reports of 39,984 people who have side effects when taking Yaz from the FDA, and is updated regularly.

What is Yaz?

Yaz has active ingredients of drospirenone; ethinyl estradiol. It is often used in birth control. eHealthMe is studying from 41,514 Yaz users. Check the latest studies of Yaz.

What is Tibia fracture?

Tibia fracture (fracture of lower leg bone) is found to be associated with 643 drugs and 670 conditions by eHealthMe. Check the latest studies of Tibia fracture.

On Aug, 08, 2026

39,984 people reported to have side effects when taking Yaz.
Among them, 11 people (0.03%) have Tibia fracture.

$Could Yaz cause Tibia fracture?$

Among these 11 people:

How long have people been on Yaz when they have Tibia fracture? *

What is the gender of people who have Tibia fracture when taking Yaz? *

female: 100 %
male: 0.0 %

What is the age of people who have Tibia fracture when taking Yaz? *

What are other drugs people take besides Yaz? *

What are other side effects people have besides Tibia fracture? *

Stress And Anxiety: 7 people, 63.64%
Consciousness - Decreased: 5 people, 45.45%
Speech Disorder: 5 people, 45.45%
Muscle Spasms (muscle contraction): 5 people, 45.45%
Depression: 5 people, 45.45%
Concussion (short loss of normal brain function in response to a head injury): 5 people, 45.45%
Movement - Uncoordinated: 5 people, 45.45%
Pulmonary Embolism (blockage of the main artery of the lung): 5 people, 45.45%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 5 people, 45.45%
Memory Loss: 5 people, 45.45%

What are the existing conditions these people have? *

Stress And Anxiety: 7 people, 63.64%
Migraine (headache): 5 people, 45.45%
Depression: 5 people, 45.45%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 27.27%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 27.27%
Abdominal Distension: 3 people, 27.27%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 18.18%
Osteoporosis (bones weak and more likely to break): 1 person, 9.09%
Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Yaz and have Tibia fracture?

- Check whether Tibia fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Yaz:

Yaz (41,514 reports)

Tibia fracture treatments and more:

Tibia fracture (6,376 reports)

How severe was Tibia fracture and when was it recovered:

Tibia fracture in Yaz

Expand to all the drugs that have ingredients of drospirenone; ethinyl estradiol:

Tibia fracture and drugs with ingredients of drospirenone; ethinyl estradiol (14 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Yaz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tibia fracture:

Tibia fracture (643 drugs)

Browse all the conditions that are associated with Tibia fracture:

Tibia fracture (670 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on drospirenone; ethinyl estradiol (the active ingredients of Yaz) and Yaz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.