Yondelis and Dyspnea - a phase IV clinical study of FDA data

Summary:

Dyspnea is reported as a side effect among people who take Yondelis (trabectedin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Votrient, and have Synovial sarcoma metastatic.

The phase IV clinical study analyzes which people have Dyspnea when taking Yondelis. It is created by eHealthMe based on reports of 1,220 people who have side effects when taking Yondelis from the FDA, and is updated regularly.

What is Yondelis?

Yondelis has active ingredients of trabectedin. eHealthMe is studying from 1,220 Yondelis users. Check the latest studies of Yondelis.

What is Dyspnea?

Dyspnea (difficult or laboured breathing) is found to be associated with 3,717 drugs and 6,067 conditions by eHealthMe. Check the latest studies of Dyspnea.

On Jul, 27, 2026

1,220 people reported to have side effects when taking Yondelis.
Among them, 32 people (2.62%) have Dyspnea.

Among these 32 people:

How long have people been on Yondelis when they have Dyspnea? *

What is the gender of people who have Dyspnea when taking Yondelis? *

female: 59.26 %
male: 40.74 %

What is the age of people who have Dyspnea when taking Yondelis? *

What are other drugs people take besides Yondelis? *

What are other side effects people have besides Dyspnea? *

Anaemia (lack of blood): 15 people, 46.88%
Thrombocytopenia (decrease of platelets in blood): 13 people, 40.62%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 10 people, 31.25%
Cough: 10 people, 31.25%
Alanine Aminotransferase Increased: 8 people, 25.00%
Aspartate Aminotransferase Increased: 8 people, 25.00%
Nausea (feeling of having an urge to vomit): 7 people, 21.88%
Pneumonia: 7 people, 21.88%
Blood Bilirubin Increased: 7 people, 21.88%
Fever: 7 people, 21.88%

What are the existing conditions these people have? *

Undifferentiated Sarcoma (undifferentiated cancer): 5 people, 15.62%
Synovial Sarcoma Metastatic (tumour of synovial membrane of joint spreads to other): 5 people, 15.62%
Leiomyosarcoma (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue): 4 people, 12.50%
Ovarian Cancer (cancer of ovary): 4 people, 12.50%
White Blood Cell Count Decreased: 3 people, 9.38%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 3 people, 9.38%
Fever: 3 people, 9.38%
Hypokalemia (low potassium): 3 people, 9.38%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 2 people, 6.25%
Ewing's Sarcoma (malignant small, round, blue cell tumour): 1 person, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Yondelis and have Dyspnea?

- Check whether Dyspnea is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Yondelis:

Yondelis (1,220 reports)

Dyspnea treatments and more:

Dyspnea (661,578 reports)

Browse all side effects of Yondelis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Dyspnea:

Dyspnea (3,717 drugs)

Browse all the conditions that are associated with Dyspnea:

Dyspnea (6,067 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trabectedin (the active ingredients of Yondelis) and Yondelis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.