Yondelis and Muscle aches - a phase IV clinical study of FDA data

Summary:

Muscle aches is reported as a side effect among people who take Yondelis (trabectedin), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Atenolol, and have Leiomyosarcoma metastatic.

The phase IV clinical study analyzes which people have Muscle aches when taking Yondelis. It is created by eHealthMe based on reports of 1,220 people who have side effects when taking Yondelis from the FDA, and is updated regularly.

What is Yondelis?

Yondelis has active ingredients of trabectedin. eHealthMe is studying from 1,220 Yondelis users. Check the latest studies of Yondelis.

What is Muscle aches?

Muscle aches (muscle pain) is found to be associated with 2,724 drugs and 3,747 conditions by eHealthMe. Check the latest studies of Muscle aches.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

1,220 people reported to have side effects when taking Yondelis.
Among them, 18 people (1.48%) have Muscle aches.

Among these 18 people:

How long have people been on Yondelis when they have Muscle aches? *

What is the gender of people who have Muscle aches when taking Yondelis? *

female: 81.25 %
male: 18.75 %

What is the age of people who have Muscle aches when taking Yondelis? *

What are other drugs people take besides Yondelis? *

What are other side effects people have besides Muscle aches? *

Blood Creatine Phosphokinase Increased: 12 people, 66.67%
Alanine Aminotransferase Increased: 8 people, 44.44%
Gamma-Glutamyltransferase Increased: 6 people, 33.33%
Aspartate Aminotransferase Increased: 6 people, 33.33%
Fatigue (feeling of tiredness): 5 people, 27.78%
Blood Creatinine Increased: 5 people, 27.78%
Thrombocytopenia (decrease of platelets in blood): 5 people, 27.78%
Blood Bilirubin Increased: 5 people, 27.78%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 5 people, 27.78%
White Blood Cell Count Decreased: 4 people, 22.22%

What are the existing conditions these people have? *

Leiomyosarcoma Metastatic (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue spreading to other parts): 4 people, 22.22%
Sarcoma Metastatic (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues spreads to other parts): 2 people, 11.11%
Ovarian Cancer (cancer of ovary): 2 people, 11.11%
Synovial Sarcoma Metastatic (tumour of synovial membrane of joint spreads to other): 1 person, 5.56%
Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 1 person, 5.56%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 1 person, 5.56%
Ovarian Cancer Recurrent (reoccurrence of ovary cancer): 1 person, 5.56%
Metastatic Uterine Cancer (spreadable cancer of uterus): 1 person, 5.56%
Metastases To Lung (cancer spreads to lung): 1 person, 5.56%
Lipid Metabolism Disorder (genetic disorders are caused by errors in fatty acid metabolism): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Yondelis and have Muscle aches?

- Check whether Muscle aches is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Yondelis:

Yondelis (1,220 reports)

Muscle aches treatments and more:

Muscle aches (219,259 reports)

Browse all side effects of Yondelis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle aches:

Muscle aches (2,724 drugs)

Browse all the conditions that are associated with Muscle aches:

Muscle aches (3,747 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trabectedin (the active ingredients of Yondelis) and Yondelis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.