Zaditor and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Zaditor (ketotifen fumarate), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Singulair, and have Narcolepsy.

The phase IV clinical study analyzes which people have Insomnia when taking Zaditor. It is created by eHealthMe based on reports of 4,423 people who have side effects when taking Zaditor from the FDA, and is updated regularly.

What is Zaditor?

Zaditor has active ingredients of ketotifen fumarate. It is often used in eye allergy. eHealthMe is studying from 4,448 Zaditor users. Check the latest studies of Zaditor.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,118 drugs and 5,170 conditions by eHealthMe. Check the latest studies of Insomnia.

On Jul, 13, 2026

4,423 people reported to have side effects when taking Zaditor.
Among them, 19 people (0.43%) have Insomnia.

Among these 19 people:

How long have people been on Zaditor when they have Insomnia? *

What is the gender of people who have Insomnia when taking Zaditor? *

female: 76.47 %
male: 23.53 %

What is the age of people who have Insomnia when taking Zaditor? *

What are other drugs people take besides Zaditor? *

What are other side effects people have besides Insomnia? *

Dizziness: 4 people, 21.05%
Nausea (feeling of having an urge to vomit): 4 people, 21.05%
Malaise (a feeling of general discomfort or uneasiness): 3 people, 15.79%
Haemoglobin Decreased: 3 people, 15.79%
Diarrhea: 3 people, 15.79%
Back Pain: 3 people, 15.79%
Pain In Extremity: 3 people, 15.79%
High Blood Pressure: 2 people, 10.53%
Oedema Peripheral (superficial swelling): 2 people, 10.53%
Gait Deviation: 2 people, 10.53%

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 21.05%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 21.05%
Asthma: 3 people, 15.79%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 10.53%
Osteoporosis (bones weak and more likely to break): 2 people, 10.53%
Hypersensitivity: 2 people, 10.53%
Diabetes: 2 people, 10.53%
Seasonal Allergy (allergic condition due to certain season): 2 people, 10.53%
Cardiac Failure Congestive: 1 person, 5.26%
Depression: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Zaditor and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zaditor:

Zaditor (4,448 reports)

Insomnia treatments and more:

Insomnia (438,078 reports)

Browse all side effects of Zaditor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Insomnia (3,118 drugs)

Browse all the conditions that are associated with Insomnia:

Insomnia (5,170 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ketotifen fumarate (the active ingredients of Zaditor) and Zaditor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.