Zantac 150 and Oedema peripheral - a phase IV clinical study of FDA data

Summary:

Oedema peripheral is reported as a side effect among people who take Zantac 150 (ranitidine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Coumadin, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Oedema peripheral when taking Zantac 150. It is created by eHealthMe based on reports of 5,708 people who have side effects when taking Zantac 150 from the FDA, and is updated regularly.

What is Zantac 150?

Zantac 150 has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 6,519 Zantac 150 users. Check the latest studies of Zantac 150.

What is Oedema peripheral?

Oedema peripheral (superficial swelling) is found to be associated with 2,774 drugs and 3,465 conditions by eHealthMe. Check the latest studies of Oedema peripheral.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

5,708 people reported to have side effects when taking Zantac 150.
Among them, 29 people (0.51%) have Oedema peripheral.

Could Zantac 150 cause Oedema peripheral?

Among these 29 people:

How long have people been on Zantac 150 when they have Oedema peripheral? *

What is the gender of people who have Oedema peripheral when taking Zantac 150? *

female: 35.71 %
male: 64.29 %

What is the age of people who have Oedema peripheral when taking Zantac 150? *

What are other drugs people take besides Zantac 150? *

What are other side effects people have besides Oedema peripheral? *

Itching: 8 people, 27.59%
Urticaria (rash of round, red welts on the skin that itch intensely): 5 people, 17.24%
Pain: 5 people, 17.24%
Joint Pain: 4 people, 13.79%
Rashes (redness): 3 people, 10.34%
Fever: 3 people, 10.34%
Pneumonia: 3 people, 10.34%
Pleural Effusion (water on the lungs): 3 people, 10.34%
Hypersensitivity: 3 people, 10.34%
Joint Swelling: 3 people, 10.34%

What are the existing conditions these people have? *

Stress And Anxiety: 3 people, 10.34%
High Blood Pressure: 2 people, 6.90%
Bipolar Disorder (mood disorder): 2 people, 6.90%
Multiple Myeloma (cancer of the plasma cells): 2 people, 6.90%
High Blood Cholesterol: 2 people, 6.90%
Erosive Oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time): 1 person, 3.45%
Gastritis (inflammation of stomach): 1 person, 3.45%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 3.45%
Exposure To Toxic Agent: 1 person, 3.45%
Essential Hypertension (primary hypertension): 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Zantac 150 and have Oedema peripheral?

- Check whether Oedema peripheral is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zantac 150:

Zantac 150 (6,519 reports)

Oedema peripheral treatments and more:

Oedema peripheral (172,690 reports)

Browse all side effects of Zantac 150:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema peripheral:

Oedema peripheral (2,774 drugs)

Browse all the conditions that are associated with Oedema peripheral:

Oedema peripheral (3,465 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine hydrochloride (the active ingredients of Zantac 150) and Zantac 150 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.