Zaroxolyn and Blindness - a phase IV clinical study of FDA data

Summary:

Blindness is reported as a side effect among people who take Zaroxolyn (metolazone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Diabetes.

The phase IV clinical study analyzes which people have Blindness when taking Zaroxolyn. It is created by eHealthMe based on reports of 5,225 people who have side effects when taking Zaroxolyn from the FDA, and is updated regularly.

What is Zaroxolyn?

Zaroxolyn has active ingredients of metolazone. It is often used in high blood pressure. eHealthMe is studying from 5,244 Zaroxolyn users. Check the latest studies of Zaroxolyn.

What is Blindness?

Blindness is found to be associated with 1,506 drugs and 1,990 conditions by eHealthMe. Check the latest studies of Blindness.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

5,225 people reported to have side effects when taking Zaroxolyn.
Among them, 33 people (0.63%) have Blindness.

Among these 33 people:

How long have people been on Zaroxolyn when they have Blindness? *

What is the gender of people who have Blindness when taking Zaroxolyn? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Blindness when taking Zaroxolyn? *

What are other drugs people take besides Zaroxolyn? *

What are other side effects people have besides Blindness? *

Dizziness: 14 people, 42.42%
Dyspnea (difficult or laboured breathing): 12 people, 36.36%
Pain: 12 people, 36.36%
Heart Attack: 9 people, 27.27%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 9 people, 27.27%
Stress And Anxiety: 9 people, 27.27%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 8 people, 24.24%
Nausea (feeling of having an urge to vomit): 8 people, 24.24%
Wheezing (a high-pitched whistling sound made while you breath): 7 people, 21.21%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 6 people, 18.18%

What are the existing conditions these people have? *

Pain: 4 people, 12.12%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 12.12%
Diabetes: 4 people, 12.12%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 9.09%
Neuropathy Peripheral (surface nerve damage): 2 people, 6.06%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 3.03%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 3.03%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 3.03%
Gout (uric acid crystals building up in the body): 1 person, 3.03%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Zaroxolyn and have Blindness?

- Check whether Blindness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zaroxolyn:

Zaroxolyn (5,244 reports)

Blindness treatments and more:

Blindness (45,948 reports)

Browse all side effects of Zaroxolyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blindness:

Blindness (1,506 drugs)

Browse all the conditions that are associated with Blindness:

Blindness (1,990 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metolazone (the active ingredients of Zaroxolyn) and Zaroxolyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.