Zavesca and Splenomegaly - a phase IV clinical study of FDA data

Summary:

Splenomegaly is reported as a side effect among people who take Zavesca (miglustat), especially for people who are male, 20-29 old, have been taking the drug for 6 - 12 months also take Cerezyme, and have Epilepsy.

The phase IV clinical study analyzes which people have Splenomegaly when taking Zavesca. It is created by eHealthMe based on reports of 1,202 people who have side effects when taking Zavesca from the FDA, and is updated regularly.

What is Zavesca?

Zavesca has active ingredients of miglustat. eHealthMe is studying from 1,208 Zavesca users. Check the latest studies of Zavesca.

What is Splenomegaly?

Splenomegaly (enlargement of spleen) is found to be associated with 1,111 drugs and 1,477 conditions by eHealthMe. Check the latest studies of Splenomegaly.

On Jul, 17, 2026

1,202 people reported to have side effects when taking Zavesca.
Among them, 12 people (1.0%) have Splenomegaly.

Among these 12 people:

How long have people been on Zavesca when they have Splenomegaly? *

What is the gender of people who have Splenomegaly when taking Zavesca? *

female: 50 %
male: 50 %

What is the age of people who have Splenomegaly when taking Zavesca? *

What are other drugs people take besides Zavesca? *

What are other side effects people have besides Splenomegaly? *

Thrombocytopenia (decrease of platelets in blood): 5 people, 41.67%
Hepatomegaly (abnormal enlargement of the liver): 4 people, 33.33%
Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 25.00%
Diarrhea: 3 people, 25.00%
Bone Pain: 3 people, 25.00%
Chitotriosidase Increased: 2 people, 16.67%
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 2 people, 16.67%
General Physical Health Deterioration (weak health status): 2 people, 16.67%
Weakness: 2 people, 16.67%
Disease Progression: 2 people, 16.67%

What are the existing conditions these people have? *

Sleep Disorder: 1 person, 8.33%
Lipidosis (disorder of lipid metabolism involving abnormal accumulation of lipids in the reticuloendothelial cells): 1 person, 8.33%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Zavesca and have Splenomegaly?

- Check whether Splenomegaly is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zavesca:

Zavesca (1,208 reports)

Splenomegaly treatments and more:

Splenomegaly (17,257 reports)

Browse all side effects of Zavesca:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Splenomegaly:

Splenomegaly (1,111 drugs)

Browse all the conditions that are associated with Splenomegaly:

Splenomegaly (1,477 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on miglustat (the active ingredients of Zavesca) and Zavesca (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.