Zegerid otc and Headache - a phase IV clinical study of FDA data

Summary:

Headache is reported as a side effect among people who take Zegerid otc (omeprazole; sodium bicarbonate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Promethazine, and have Immunodeficiency.

The phase IV clinical study analyzes which people have Headache when taking Zegerid otc. It is created by eHealthMe based on reports of 1,167 people who have side effects when taking Zegerid otc from the FDA, and is updated regularly.

What is Zegerid otc?

Zegerid otc has active ingredients of omeprazole; sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 1,211 Zegerid otc users. Check the latest studies of Zegerid otc.

What is Headache?

Headache (pain in head) is found to be associated with 3,754 drugs and 5,772 conditions by eHealthMe. Check the latest studies of Headache.

On Jul, 20, 2026

1,167 people reported to have side effects when taking Zegerid otc.
Among them, 22 people (1.89%) have Headache.

Among these 22 people:

How long have people been on Zegerid otc when they have Headache? *

What is the gender of people who have Headache when taking Zegerid otc? *

female: 89.47 %
male: 10.53 %

What is the age of people who have Headache when taking Zegerid otc? *

What are other drugs people take besides Zegerid otc? *

Promethazine: 4 people, 18.18%
Acetaminophen: 3 people, 13.64%
Epinephrine: 3 people, 13.64%
Zanaflex: 3 people, 13.64%
Metformin Hydrochloride: 3 people, 13.64%
Metformin: 3 people, 13.64%
Lyrica: 3 people, 13.64%
Buspirone Hcl: 3 people, 13.64%
Prandin: 3 people, 13.64%
Promethazine Hydrochloride: 3 people, 13.64%

What are other side effects people have besides Headache? *

Nausea (feeling of having an urge to vomit): 7 people, 31.82%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 22.73%
Nausea And Vomiting: 4 people, 18.18%
Tinnitus (a ringing in the ears): 4 people, 18.18%
Hypoaesthesia (reduced sense of touch or sensation): 3 people, 13.64%
Oral Infection: 3 people, 13.64%
Otitis (ear infection): 3 people, 13.64%
Pain In Extremity: 3 people, 13.64%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 13.64%
Pneumonia: 3 people, 13.64%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 3 people, 13.64%
Immunodeficiency: 3 people, 13.64%
Indigestion: 2 people, 9.09%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 9.09%
High Blood Pressure: 2 people, 9.09%
Rashes (redness): 1 person, 4.55%
Gout (uric acid crystals building up in the body): 1 person, 4.55%
Blood Pressure Abnormal: 1 person, 4.55%
Cystic Fibrosis (disease of the secretary glands): 1 person, 4.55%
Depression: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Zegerid otc and have Headache?

- Check whether Headache is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zegerid otc:

Zegerid otc (1,211 reports)

Headache treatments and more:

Headache (756,642 reports)

How severe was Headache and when was it recovered:

Headache in Zegerid otc

Expand to all the drugs that have ingredients of omeprazole; sodium bicarbonate:

Headache and drugs with ingredients of omeprazole; sodium bicarbonate (232 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zegerid otc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Headache:

Headache (3,754 drugs)

Browse all the conditions that are associated with Headache:

Headache (5,772 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on omeprazole; sodium bicarbonate (the active ingredients of Zegerid otc) and Zegerid otc (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.