Zenpep and Obstructive airways disorder - a phase IV clinical study of FDA data

Summary:

Obstructive airways disorder is reported as a side effect among people who take Zenpep (pancrelipase (amylase;lipase;protease)), especially for people who are male, 30-39 old, have been taking the drug for 1 - 2 years also take Pulmozyme, and have Cystic fibrosis.

The phase IV clinical study analyzes which people have Obstructive airways disorder when taking Zenpep. It is created by eHealthMe based on reports of 5,490 people who have side effects when taking Zenpep from the FDA, and is updated regularly.

What is Zenpep?

Zenpep has active ingredients of pancrelipase (amylase;lipase;protease). eHealthMe is studying from 5,529 Zenpep users. Check the latest studies of Zenpep.

What is Obstructive airways disorder?

Obstructive airways disorder (a progressive disease that makes it hard to breathe) is found to be associated with 889 drugs and 1,233 conditions by eHealthMe. Check the latest studies of Obstructive airways disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 20, 2026

5,490 people reported to have side effects when taking Zenpep.
Among them, 11 people (0.2%) have Obstructive airways disorder.

Could Zenpep cause Obstructive airways disorder?

Among these 11 people:

How long have people been on Zenpep when they have Obstructive airways disorder? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Obstructive airways disorder when taking Zenpep? *

  • female: 18.18 %
  • male: 81.82 %

What is the age of people who have Obstructive airways disorder when taking Zenpep? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 20 %
  • 20-29: 10 %
  • 30-39: 50 %
  • 40-49: 0.0 %
  • 50-59: 10 %
  • 60+: 10 %

What are other drugs people take besides Zenpep? *

  1. Pulmozyme: 11 people, 100.00%
  2. Tobi Podhaler: 10 people, 90.91%
  3. Cayston: 8 people, 72.73%
  4. Humalog: 7 people, 63.64%
  5. Insulin: 5 people, 45.45%
  6. Tobi: 5 people, 45.45%
  7. Magnesium: 4 people, 36.36%
  8. Heparin: 3 people, 27.27%
  9. Vitamin D3: 3 people, 27.27%
  10. Ventolin Hfa: 3 people, 27.27%

What are other side effects people have besides Obstructive airways disorder? *

  1. Cough: 8 people, 72.73%
  2. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 8 people, 72.73%
  3. Dyspnea (difficult or laboured breathing): 7 people, 63.64%
  4. Sputum Discolored: 6 people, 54.55%
  5. Productive Cough: 6 people, 54.55%
  6. Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 6 people, 54.55%
  7. Blood Pressure Systolic Decreased: 5 people, 45.45%
  8. Chest Pain: 5 people, 45.45%
  9. Drug Resistance (reduction in effectiveness of a drug): 5 people, 45.45%
  10. Pulmonary Oedema (fluid accumulation in the lungs): 5 people, 45.45%

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 10 people, 90.91%
  2. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 7 people, 63.64%
  3. Cystic Fibrosis Lung (fibrosis with cyst in the lung): 6 people, 54.55%
  4. Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 5 people, 45.45%
  5. Cystic Fibrosis Related Diabetes: 5 people, 45.45%
  6. Allergic Rhinitis: 3 people, 27.27%
  7. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 9.09%
  8. Pneumonia Pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa): 1 person, 9.09%
  9. Pancreatic Insufficiency: 1 person, 9.09%
  10. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Zenpep and have Obstructive airways disorder?

- Check whether Obstructive airways disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zenpep:

Obstructive airways disorder treatments and more:

How severe was Obstructive airways disorder and when was it recovered:

Expand to all the drugs that have ingredients of pancrelipase (amylase;lipase;protease):

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zenpep:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Obstructive airways disorder:

Browse all the conditions that are associated with Obstructive airways disorder:


How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) (the active ingredients of Zenpep) and Zenpep (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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