Zenpep and Small intestinal obstruction - a phase IV clinical study of FDA data

Summary:

Small intestinal obstruction is reported as a side effect among people who take Zenpep (pancrelipase (amylase;lipase;protease)), especially for people who are female, 0-1 old, have been taking the drug for 1 - 6 months also take Magnesium, and have Cystic fibrosis.

The phase IV clinical study analyzes which people have Small intestinal obstruction when taking Zenpep. It is created by eHealthMe based on reports of 5,490 people who have side effects when taking Zenpep from the FDA, and is updated regularly.

What is Zenpep?

Zenpep has active ingredients of pancrelipase (amylase;lipase;protease). eHealthMe is studying from 5,529 Zenpep users. Check the latest studies of Zenpep.

What is Small intestinal obstruction?

Small intestinal obstruction (blockage in small intestine) is found to be associated with 1,035 drugs and 986 conditions by eHealthMe. Check the latest studies of Small intestinal obstruction.

On Aug, 11, 2026

5,490 people reported to have side effects when taking Zenpep.
Among them, 16 people (0.29%) have Small intestinal obstruction.

Could Zenpep cause Small intestinal obstruction?

Among these 16 people:

How long have people been on Zenpep when they have Small intestinal obstruction? *

What is the gender of people who have Small intestinal obstruction when taking Zenpep? *

female: 75 %
male: 25 %

What is the age of people who have Small intestinal obstruction when taking Zenpep? *

What are other drugs people take besides Zenpep? *

What are other side effects people have besides Small intestinal obstruction? *

Intestinal Obstruction: 8 people, 50.00%
Upper Respiratory Tract Infection: 5 people, 31.25%
Intestinal Ischaemia (decreased supply of oxygenated blood to the intestines): 4 people, 25.00%
Foetal Growth Restriction (poor growth of a baby while in the mother's womb during pregnancy): 4 people, 25.00%
Brain Natriuretic Peptide Increased: 4 people, 25.00%
Cardiac Murmur (an heart sound in valve abnormality): 4 people, 25.00%
Neonatal Hypoxia (lack of oxygen in neonate): 4 people, 25.00%
Nasal Flaring (nostrils widen while a person is breathing): 4 people, 25.00%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 4 people, 25.00%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 4 people, 25.00%

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 7 people, 43.75%
Nausea (feeling of having an urge to vomit): 3 people, 18.75%
Vomiting In Pregnancy: 2 people, 12.50%
Pain: 2 people, 12.50%
Immunodeficiency Common Variable: 2 people, 12.50%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 2 people, 12.50%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 6.25%
Stress And Anxiety: 1 person, 6.25%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 6.25%
Pancreatic Carcinoma (pancreatic cancer): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Zenpep and have Small intestinal obstruction?

- Check whether Small intestinal obstruction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zenpep:

Zenpep (5,529 reports)

Small intestinal obstruction treatments and more:

Small intestinal obstruction (15,333 reports)

How severe was Small intestinal obstruction and when was it recovered:

Small intestinal obstruction in Zenpep

Expand to all the drugs that have ingredients of pancrelipase (amylase;lipase;protease):

Small intestinal obstruction and drugs with ingredients of pancrelipase (amylase;lipase;protease)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zenpep:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Small intestinal obstruction:

Small intestinal obstruction (1,035 drugs)

Browse all the conditions that are associated with Small intestinal obstruction:

Small intestinal obstruction (986 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) (the active ingredients of Zenpep) and Zenpep (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.