Zeposia and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is reported as a side effect among people who take Zeposia (ozanimod hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Lyrica, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Joint swelling when taking Zeposia. It is created by eHealthMe based on reports of 6,371 people who have side effects when taking Zeposia from the FDA, and is updated regularly.

What is Zeposia?

Zeposia has active ingredients of ozanimod hydrochloride. eHealthMe is studying from 6,372 Zeposia users. Check the latest studies of Zeposia.

What is Joint swelling?

Joint swelling is found to be associated with 2,120 drugs and 2,938 conditions by eHealthMe. Check the latest studies of Joint swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

6,371 people reported to have side effects when taking Zeposia.
Among them, 36 people (0.57%) have Joint swelling.

Among these 36 people:

How long have people been on Zeposia when they have Joint swelling? *

What is the gender of people who have Joint swelling when taking Zeposia? *

female: 88.89 %
male: 11.11 %

What is the age of people who have Joint swelling when taking Zeposia? *

What are other drugs people take besides Zeposia? *

What are other side effects people have besides Joint swelling? *

Peripheral Swelling: 9 people, 25.00%
Joint Pain: 6 people, 16.67%
Rashes (redness): 4 people, 11.11%
Fall: 4 people, 11.11%
Dizziness: 3 people, 8.33%
High Blood Pressure: 2 people, 5.56%
Headache (pain in head): 2 people, 5.56%
Fatigue (feeling of tiredness): 2 people, 5.56%
Muscle Aches (muscle pain): 2 people, 5.56%
Nausea And Vomiting: 2 people, 5.56%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 17 people, 47.22%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 10 people, 27.78%
Secondary Progressive Multiple Sclerosis (a stage of ms which comes after relapsing remitting ms in many cases): 2 people, 5.56%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 2 people, 5.56%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.56%
Clinically Isolated Syndrome (individual's first neurological episode, caused by inflammation or demyelination of nerve tissue): 2 people, 5.56%
Proctitis Ulcerative (inflammation of the rectum and anus ulcerative): 1 person, 2.78%
Multiple Myeloma (cancer of the plasma cells): 1 person, 2.78%
Colitis (inflammation of colon): 1 person, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Zeposia and have Joint swelling?

- Check whether Joint swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zeposia:

Zeposia (6,372 reports)

Joint swelling treatments and more:

Joint swelling (143,797 reports)

Browse all side effects of Zeposia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint swelling:

Joint swelling (2,120 drugs)

Browse all the conditions that are associated with Joint swelling:

Joint swelling (2,938 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ozanimod hydrochloride (the active ingredients of Zeposia) and Zeposia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.