Zerit and Agitation - a phase IV clinical study of FDA data
Summary:
Agitation is reported as a side effect among people who take Zerit (stavudine), especially for people who are male, 0-1 old, have been taking the drug for 1 - 6 months also take Epivir, and have Hiv infection.
The phase IV clinical study analyzes which people have Agitation when taking Zerit. It is created by eHealthMe based on reports of 9,900 people who have side effects when taking Zerit from the FDA, and is updated regularly.
What is Zerit?
Zerit has active ingredients of stavudine. eHealthMe is studying from 9,912 Zerit users. Check the latest studies of Zerit.
What is Agitation?
Agitation (state of anxiety or nervous excitement) is found to be associated with 2,280 drugs and 3,314 conditions by eHealthMe. Check the latest studies of Agitation.
9,900 people reported to have side effects when taking Zerit.
Among them, 75 people (0.76%) have Agitation.

Among these 75 people:
How long have people been on Zerit when they have Agitation? *
- < 1 month: 12 %
- 1 - 6 months: 48 %
- 6 - 12 months: 32 %
- 1 - 2 years: 8 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Agitation when taking Zerit? *
- female: 28 %
- male: 72 %
What is the age of people who have Agitation when taking Zerit? *
- 0-1: 34.38 %
- 2-9: 4.69 %
- 10-19: 0.0 %
- 20-29: 12.5 %
- 30-39: 14.06 %
- 40-49: 12.5 %
- 50-59: 18.75 %
- 60+: 3.12 %
What are other drugs people take besides Zerit? *
- Epivir: 47 people, 62.67%
- Retrovir: 28 people, 37.33%
- Videx: 28 people, 37.33%
- Viramune: 23 people, 30.67%
- Crixivan: 20 people, 26.67%
- Invirase: 18 people, 24.00%
- Bactrim: 17 people, 22.67%
- Viracept: 14 people, 18.67%
- Sustiva: 12 people, 16.00%
- Kaletra: 10 people, 13.33%
What are other side effects people have besides Agitation? *
- Blood Lactic Acid Increased: 24 people, 32.00%
- Hypertriglyceridaemia (excess of triglycerides in the blood): 14 people, 18.67%
- Febrile Convulsion (a convulsion associated with a significant rise in body temperature): 9 people, 12.00%
- Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 9 people, 12.00%
- Lactic Acidosis (low ph in body tissues): 9 people, 12.00%
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 9 people, 12.00%
- Anaemia (lack of blood): 9 people, 12.00%
- Hepatomegaly (abnormal enlargement of the liver): 8 people, 10.67%
- Cytomegalovirus Infection: 8 people, 10.67%
- Speech Disorder: 8 people, 10.67%
What are the existing conditions these people have? *
- Hiv Infection: 22 people, 29.33%
- Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 4 people, 5.33%
- High Blood Pressure: 2 people, 2.67%
- Stress And Anxiety: 2 people, 2.67%
- Pulmonary Tuberculosis (lungs tuberculosis): 2 people, 2.67%
- Insomnia (sleeplessness): 2 people, 2.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 1.33%
- Atonic Seizures (minor type of seizure): 1 person, 1.33%
- Cytomegalovirus Infection: 1 person, 1.33%
- Depression: 1 person, 1.33%
* Approximation only. Some reports may have incomplete information.
Do you take Zerit and have Agitation?
- Check whether Agitation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Zerit:
- Zerit (9,912 reports)
Agitation treatments and more:
- Agitation (142,107 reports)
How severe was Agitation and when was it recovered:
Expand to all the drugs that have ingredients of stavudine:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zerit:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Agitation:
- Agitation (2,280 drugs)
Browse all the conditions that are associated with Agitation:
- Agitation (3,314 conditions)
Related publications that referenced our studies
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on stavudine (the active ingredients of Zerit) and Zerit (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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