Zestoretic and Emesis - a phase IV clinical study of FDA data

Summary:

Emesis is reported as a side effect among people who take Zestoretic (hydrochlorothiazide; lisinopril), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Aspirin, and have Pain.

The phase IV clinical study analyzes which people have Emesis when taking Zestoretic. It is created by eHealthMe based on reports of 4,193 people who have side effects when taking Zestoretic from the FDA, and is updated regularly.

What is Zestoretic?

Zestoretic has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 4,342 Zestoretic users. Check the latest studies of Zestoretic.

What is Emesis?

Emesis (process of vomiting) is found to be associated with 4,469 drugs and 5,757 conditions by eHealthMe. Check the latest studies of Emesis.

On Jul, 07, 2026

4,193 people reported to have side effects when taking Zestoretic.
Among them, 109 people (2.6%) have Emesis.

Among these 109 people:

* Approximation only. Some reports may have incomplete information.

Do you take Zestoretic and have Emesis?

- Check whether Emesis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zestoretic:

Zestoretic (4,342 reports)

Emesis treatments and more:

Emesis (529,395 reports)

How severe was Emesis and when was it recovered:

Emesis in Zestoretic

Expand to all the drugs that have ingredients of hydrochlorothiazide; lisinopril:

Emesis and drugs with ingredients of hydrochlorothiazide; lisinopril (708 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zestoretic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Emesis:

Emesis (4,469 drugs)

Browse all the conditions that are associated with Emesis:

Emesis (5,757 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; lisinopril (the active ingredients of Zestoretic) and Zestoretic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.