Zestril and Eye pain - a phase IV clinical study of FDA data

Summary:

Eye pain is reported as a side effect among people who take Zestril (lisinopril), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prinivil, and have Mania.

The phase IV clinical study analyzes which people have Eye pain when taking Zestril. It is created by eHealthMe based on reports of 21,786 people who have side effects when taking Zestril from the FDA, and is updated regularly.

What is Zestril?

Zestril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 22,273 Zestril users. Check the latest studies of Zestril.

What is Eye pain?

Eye pain is found to be associated with 1,762 drugs and 2,465 conditions by eHealthMe. Check the latest studies of Eye pain.



On Jul, 04, 2026

21,786 people reported to have side effects when taking Zestril.
Among them, 74 people (0.34%) have Eye pain.

Could Zestril cause Eye pain?

Among these 74 people:

How long have people been on Zestril when they have Eye pain? *

  • < 1 month: 85.71 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 14.29 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Eye pain when taking Zestril? *

  • female: 54.79 %
  • male: 45.21 %

What is the age of people who have Eye pain when taking Zestril? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 21.74 %
  • 50-59: 17.39 %
  • 60+: 60.87 %

What are other drugs people take besides Zestril? *

  1. Prinivil: 17 people, 22.97%
  2. Coreg: 14 people, 18.92%
  3. Lipitor: 14 people, 18.92%
  4. Glyburide: 12 people, 16.22%
  5. Neurontin: 11 people, 14.86%
  6. Glucophage: 11 people, 14.86%
  7. Zocor: 10 people, 13.51%
  8. Vitamin D3: 8 people, 10.81%
  9. Lyrica: 8 people, 10.81%
  10. Lasix: 8 people, 10.81%

What are other side effects people have besides Eye pain? *

  1. Headache (pain in head): 30 people, 40.54%
  2. Chest Pain: 25 people, 33.78%
  3. Vision Blurred: 21 people, 28.38%
  4. Fatigue (feeling of tiredness): 21 people, 28.38%
  5. Hypoaesthesia (reduced sense of touch or sensation): 20 people, 27.03%
  6. Nausea (feeling of having an urge to vomit): 16 people, 21.62%
  7. Dyspnea (difficult or laboured breathing): 16 people, 21.62%
  8. Chills (felling of cold): 14 people, 18.92%
  9. Malaise (a feeling of general discomfort or uneasiness): 13 people, 17.57%
  10. Dizziness: 13 people, 17.57%

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 8.11%
  2. Mania (a state of abnormally elevated or irritable mood): 6 people, 8.11%
  3. Muscle Spasms (muscle contraction): 5 people, 6.76%
  4. Pain: 5 people, 6.76%
  5. Wheezing (a high-pitched whistling sound made while you breath): 4 people, 5.41%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 5.41%
  7. Herpes Zoster: 4 people, 5.41%
  8. Prostate Cancer Metastatic: 3 people, 4.05%
  9. Diabetes: 3 people, 4.05%
  10. Multiple Myeloma (cancer of the plasma cells): 2 people, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Zestril and have Eye pain?

- Check whether Eye pain is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zestril:

Eye pain treatments and more:

How severe was Eye pain and when was it recovered:

Expand to all the drugs that have ingredients of lisinopril:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zestril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eye pain:

Browse all the conditions that are associated with Eye pain:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Zestril) and Zestril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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