Zestril and Hernia - a phase IV clinical study of FDA data

Summary:

Hernia is reported as a side effect among people who take Zestril (lisinopril), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Dilaudid, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Hernia when taking Zestril. It is created by eHealthMe based on reports of 21,786 people who have side effects when taking Zestril from the FDA, and is updated regularly.

What is Zestril?

Zestril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 22,273 Zestril users. Check the latest studies of Zestril.

What is Hernia?

Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle) is found to be associated with 1,311 drugs and 1,497 conditions by eHealthMe. Check the latest studies of Hernia.



On Jul, 12, 2026

21,786 people reported to have side effects when taking Zestril.
Among them, 87 people (0.4%) have Hernia.

Could Zestril cause Hernia?

Among these 87 people:

How long have people been on Zestril when they have Hernia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

What is the gender of people who have Hernia when taking Zestril? *

  • female: 37.21 %
  • male: 62.79 %

What is the age of people who have Hernia when taking Zestril? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 10.77 %
  • 50-59: 27.69 %
  • 60+: 61.54 %

What are other drugs people take besides Zestril? *

  1. Dilaudid: 26 people, 29.89%
  2. Zometa: 25 people, 28.74%
  3. Prednisone: 25 people, 28.74%
  4. Gabapentin: 24 people, 27.59%
  5. Amoxicillin: 23 people, 26.44%
  6. Percocet: 22 people, 25.29%
  7. Acetaminophen: 22 people, 25.29%
  8. Lisinopril: 21 people, 24.14%
  9. Chlorhexidine Gluconate: 20 people, 22.99%
  10. Prilosec: 19 people, 21.84%

What are other side effects people have besides Hernia? *

  1. Stress And Anxiety: 36 people, 41.38%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 30 people, 34.48%
  3. Pain: 28 people, 32.18%
  4. Injury: 26 people, 29.89%
  5. Joint Pain: 26 people, 29.89%
  6. Osteonecrosis Of Jaw (death of bone of jaw): 25 people, 28.74%
  7. Depression: 25 people, 28.74%
  8. Dyspnea (difficult or laboured breathing): 24 people, 27.59%
  9. Chest Pain: 21 people, 24.14%
  10. Cough: 21 people, 24.14%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 12 people, 13.79%
  2. Joint Pain: 8 people, 9.20%
  3. High Blood Cholesterol: 8 people, 9.20%
  4. Diabetes: 6 people, 6.90%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 6.90%
  6. Pain: 5 people, 5.75%
  7. Osteoporosis (bones weak and more likely to break): 5 people, 5.75%
  8. Depression: 5 people, 5.75%
  9. Urinary Tract Infection: 3 people, 3.45%
  10. Muscle Spasms (muscle contraction): 3 people, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Zestril and have Hernia?

- Check whether Hernia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zestril:

Hernia treatments and more:

How severe was Hernia and when was it recovered:

Expand to all the drugs that have ingredients of lisinopril:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zestril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hernia:

Browse all the conditions that are associated with Hernia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Zestril) and Zestril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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