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Zestril and Sinus congestion - a phase IV clinical study of FDA data

Summary:

Sinus congestion is reported as a side effect among people who take Zestril (lisinopril), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Prilosec, and have Pain.

The phase IV clinical study analyzes which people have Sinus congestion when taking Zestril. It is created by eHealthMe based on reports of 21,786 people who have side effects when taking Zestril from the FDA, and is updated regularly.

What is Zestril?

Zestril has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 22,273 Zestril users. Check the latest studies of Zestril.

What is Sinus congestion?

Sinus congestion (blockage of sinus) is found to be associated with 1,005 drugs and 955 conditions by eHealthMe. Check the latest studies of Sinus congestion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

21,786 people reported to have side effects when taking Zestril.
Among them, 48 people (0.22%) have Sinus congestion.

Could Zestril cause Sinus congestion?

Among these 48 people:

How long have people been on Zestril when they have Sinus congestion? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Sinus congestion when taking Zestril? *

  • female: 62.5 %
  • male: 37.5 %

What is the age of people who have Sinus congestion when taking Zestril? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 23.26 %
  • 40-49: 9.3 %
  • 50-59: 9.3 %
  • 60+: 58.14 %

What are other drugs people take besides Zestril? *

  1. Prilosec: 16 people, 33.33%
  2. Coumadin: 15 people, 31.25%
  3. Lasix: 14 people, 29.17%
  4. Aspirin: 13 people, 27.08%
  5. Effexor: 10 people, 20.83%
  6. Furosemide: 10 people, 20.83%
  7. Prevacid: 10 people, 20.83%
  8. Lorazepam: 10 people, 20.83%
  9. Norvasc: 10 people, 20.83%
  10. Albuterol: 9 people, 18.75%

What are other side effects people have besides Sinus congestion? *

  1. Dyspnea (difficult or laboured breathing): 19 people, 39.58%
  2. Chest Pain: 18 people, 37.50%
  3. Headache (pain in head): 17 people, 35.42%
  4. Weakness: 16 people, 33.33%
  5. Hypoaesthesia (reduced sense of touch or sensation): 16 people, 33.33%
  6. Muscle Spasms (muscle contraction): 15 people, 31.25%
  7. Weight Decreased: 15 people, 31.25%
  8. Nausea (feeling of having an urge to vomit): 15 people, 31.25%
  9. Stress And Anxiety: 15 people, 31.25%
  10. Fall: 14 people, 29.17%

What are the existing conditions these people have? *

  1. Pain: 11 people, 22.92%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 12.50%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 10.42%
  4. Oedema Peripheral (superficial swelling): 4 people, 8.33%
  5. Infection: 4 people, 8.33%
  6. Dyspnea (difficult or laboured breathing): 4 people, 8.33%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 8.33%
  8. Gastric Disorder (disease of stomach): 4 people, 8.33%
  9. Cardiac Failure: 4 people, 8.33%
  10. Hypersensitivity: 4 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Zestril and have Sinus congestion?

- Check whether Sinus congestion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zestril:

Sinus congestion treatments and more:

How severe was Sinus congestion and when was it recovered:

Expand to all the drugs that have ingredients of lisinopril:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zestril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus congestion:

Browse all the conditions that are associated with Sinus congestion:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lisinopril (the active ingredients of Zestril) and Zestril (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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