Zide and Orgasmic dysfunction - a phase IV clinical study of FDA data

Summary:

Orgasmic dysfunction is reported as a side effect among people who take Zide (hydrochlorothiazide), especially for people who are 60+ old, also take Viagra, and have Depression.

The phase IV clinical study analyzes which people have Orgasmic dysfunction when taking Zide. It is created by eHealthMe based on reports of 178,473 people who have side effects when taking Zide from the FDA, and is updated regularly.

What is Zide?

Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,239 Zide users. Check the latest studies of Zide.

What is Orgasmic dysfunction?

Orgasmic dysfunction (not getting orgasm) is found to be associated with 247 drugs and 562 conditions by eHealthMe. Check the latest studies of Orgasmic dysfunction.

On Apr, 17, 2026

178,473 people reported to have side effects when taking Zide.
Among them, 15 people (0.01%) have Orgasmic dysfunction.

Among these 15 people:

What is the age of people who have Orgasmic dysfunction when taking Zide? *

What are other drugs people take besides Zide? *

What are other side effects people have besides Orgasmic dysfunction? *

Headache (pain in head): 5 people, 33.33%
Feeling Abnormal: 4 people, 26.67%
Stress And Anxiety: 4 people, 26.67%
Erection Problems: 4 people, 26.67%
Fatigue (feeling of tiredness): 4 people, 26.67%
Muscle Spasms (muscle contraction): 4 people, 26.67%
Constipation: 4 people, 26.67%
Agitation (state of anxiety or nervous excitement): 4 people, 26.67%
Autoimmune Disorder (a condition in which the immune system attacks the body's normal substances and tissue): 3 people, 20.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 20.00%

What are the existing conditions these people have? *

Depression: 4 people, 26.67%
Pain: 3 people, 20.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 20.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 20.00%
High Blood Cholesterol: 2 people, 13.33%
Blood Pressure Abnormal: 2 people, 13.33%
Stress And Anxiety: 1 person, 6.67%
Spinal Decompression (relief of pressure on one or many pinched nerves (neural impingement) of the spinal column): 1 person, 6.67%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 6.67%
Nerve Injury: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Zide and have Orgasmic dysfunction?

- Check whether Orgasmic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zide:

Zide (183,239 reports)

Browse all side effects of Zide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Orgasmic dysfunction:

Orgasmic dysfunction (247 drugs)

Browse all the conditions that are associated with Orgasmic dysfunction:

Orgasmic dysfunction (562 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Zide) and Zide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.