Zide and Thrombophlebitis superficial - a phase IV clinical study of FDA data

Summary:

Thrombophlebitis superficial is reported as a side effect among people who take Zide (hydrochlorothiazide), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Yasmin, and have Pain.

The phase IV clinical study analyzes which people have Thrombophlebitis superficial when taking Zide. It is created by eHealthMe based on reports of 178,473 people who have side effects when taking Zide from the FDA, and is updated regularly.

What is Zide?

Zide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 183,247 Zide users. Check the latest studies of Zide.

What is Thrombophlebitis superficial?

Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot) is found to be associated with 516 drugs and 700 conditions by eHealthMe. Check the latest studies of Thrombophlebitis superficial.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

178,473 people reported to have side effects when taking Zide.
Among them, 69 people (0.04%) have Thrombophlebitis superficial.

Could Zide cause Thrombophlebitis superficial?

Among these 69 people:

How long have people been on Zide when they have Thrombophlebitis superficial? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 40 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 40 %
  • 10+ years: 20 %

What is the gender of people who have Thrombophlebitis superficial when taking Zide? *

  • female: 65.22 %
  • male: 34.78 %

What is the age of people who have Thrombophlebitis superficial when taking Zide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.02 %
  • 30-39: 17.54 %
  • 40-49: 12.28 %
  • 50-59: 24.56 %
  • 60+: 38.6 %

What are other drugs people take besides Zide? *

  1. Yasmin: 17 people, 24.64%
  2. Yaz: 15 people, 21.74%
  3. Amlodipine: 10 people, 14.49%
  4. Prednisolone: 8 people, 11.59%
  5. Cyclophosphamide: 7 people, 10.14%
  6. Lortab: 7 people, 10.14%
  7. Revlimid: 7 people, 10.14%
  8. Atacand: 7 people, 10.14%
  9. Lyrica: 7 people, 10.14%
  10. Vitamin C: 7 people, 10.14%

What are other side effects people have besides Thrombophlebitis superficial? *

  1. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 26 people, 37.68%
  2. Head Injury: 13 people, 18.84%
  3. Joint Pain: 13 people, 18.84%
  4. Pain: 11 people, 15.94%
  5. Nausea (feeling of having an urge to vomit): 11 people, 15.94%
  6. Pulmonary Embolism (blockage of the main artery of the lung): 11 people, 15.94%
  7. Nausea And Vomiting: 11 people, 15.94%
  8. Pain In Extremity: 8 people, 11.59%
  9. Haematoma (collection of blood outside the blood vessels): 8 people, 11.59%
  10. Gait Disturbance: 8 people, 11.59%

What are the existing conditions these people have? *

  1. Pain: 16 people, 23.19%
  2. Polymyalgia Rheumatica (pain in many muscles): 7 people, 10.14%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 8.70%
  4. Insomnia (sleeplessness): 6 people, 8.70%
  5. Multiple Myeloma (cancer of the plasma cells): 5 people, 7.25%
  6. Temporal Arteritis (inflammation and damage to blood vessels that supply the head area): 5 people, 7.25%
  7. Birth Control: 5 people, 7.25%
  8. Malignant Lymphoid Neoplasm (malignant growth or tumour caused by abnormal and uncontrolled cell division in lymph node): 5 people, 7.25%
  9. Osteoporosis (bones weak and more likely to break): 4 people, 5.80%
  10. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 3 people, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Zide and have Thrombophlebitis superficial?

- Check whether Thrombophlebitis superficial is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zide:

  • Zide (183,247 reports)

Thrombophlebitis superficial treatments and more:

How severe was Thrombophlebitis superficial and when was it recovered:

Expand to all the drugs that have ingredients of hydrochlorothiazide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thrombophlebitis superficial:

Browse all the conditions that are associated with Thrombophlebitis superficial:


How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Zide) and Zide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: