Zidovudine and Enzyme abnormality - a phase IV clinical study of FDA data

Summary:

Enzyme abnormality is reported as a side effect among people who take Zidovudine (zidovudine), especially for people who are male, 0-1 old, have been taking the drug for < 1 month also take Lamivudine, and have Direct infection transmission.

The phase IV clinical study analyzes which people have Enzyme abnormality when taking Zidovudine. It is created by eHealthMe based on reports of 10,506 people who have side effects when taking Zidovudine from the FDA, and is updated regularly.

What is Zidovudine?

Zidovudine has active ingredients of zidovudine. eHealthMe is studying from 10,517 Zidovudine users. Check the latest studies of Zidovudine.

What is Enzyme abnormality?

Enzyme abnormality is found to be associated with 110 drugs and 337 conditions by eHealthMe. Check the latest studies of Enzyme abnormality.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

10,506 people reported to have side effects when taking Zidovudine.
Among them, 11 people (0.1%) have Enzyme abnormality.

Could Zidovudine cause Enzyme abnormality?

Among these 11 people:

How long have people been on Zidovudine when they have Enzyme abnormality? *

What is the gender of people who have Enzyme abnormality when taking Zidovudine? *

female: 44.44 %
male: 55.56 %

What is the age of people who have Enzyme abnormality when taking Zidovudine? *

What are other drugs people take besides Zidovudine? *

What are other side effects people have besides Enzyme abnormality? *

Nuclear Magnetic Resonance Imaging Abnormal: 4 people, 36.36%
Cerebral Atrophy (decrement in size of brain): 3 people, 27.27%
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs): 3 people, 27.27%
Mental Retardation Severity Unspecified (problems with learning and developing severity unspecified): 3 people, 27.27%
Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 2 people, 18.18%
Febrile Convulsion (a convulsion associated with a significant rise in body temperature): 2 people, 18.18%
Hemiparesis (weakness on one side of the body): 2 people, 18.18%
Drug Exposure During Pregnancy: 2 people, 18.18%
Lactic Acidosis (low ph in body tissues): 2 people, 18.18%
Liver Function Tests Nos Abnormal: 2 people, 18.18%

What are the existing conditions these people have? *

Direct Infection Transmission: 3 people, 27.27%

* Approximation only. Some reports may have incomplete information.

Do you take Zidovudine and have Enzyme abnormality?

- Check whether Enzyme abnormality is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zidovudine:

Zidovudine (10,517 reports)

Browse all side effects of Zidovudine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Enzyme abnormality:

Enzyme abnormality (110 drugs)

Browse all the conditions that are associated with Enzyme abnormality:

Enzyme abnormality (337 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zidovudine (the active ingredients of Zidovudine) and Zidovudine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.