Zimovane and Insomnia exacerbated - a phase IV clinical study of FDA data

Summary:

Insomnia exacerbated is reported as a side effect among people who take Zimovane (eszopiclone), especially for people who are female, 30-39 old, also take Prozac, and have Depression.

The phase IV clinical study analyzes which people have Insomnia exacerbated when taking Zimovane. It is created by eHealthMe based on reports of 390 people who have side effects when taking Zimovane from the FDA, and is updated regularly.

What is Zimovane?

Zimovane has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 523 Zimovane users. Check the latest studies of Zimovane.

What is Insomnia exacerbated?

Insomnia exacerbated (severe sleeplessness) is found to be associated with 2,648 drugs and 974 conditions by eHealthMe. Check the latest studies of Insomnia exacerbated.

On Jul, 12, 2026

390 people reported to have side effects when taking Zimovane.
Among them, 38 people (9.74%) have Insomnia exacerbated.

Could Zimovane cause Insomnia exacerbated?

Among these 38 people:

What is the gender of people who have Insomnia exacerbated when taking Zimovane? *

female: 56.25 %
male: 43.75 %

What is the age of people who have Insomnia exacerbated when taking Zimovane? *

What are other drugs people take besides Zimovane? *

What are other side effects people have besides Insomnia exacerbated? *

Nausea (feeling of having an urge to vomit): 28 people, 73.68%
Dizziness: 27 people, 71.05%
Nightmares (unpleasant dreams): 27 people, 71.05%
Suicidal Ideation: 27 people, 71.05%
Tremor (trembling or shaking movements in one or more parts of your body): 27 people, 71.05%
Panic Disorder: 25 people, 65.79%
Agitation (state of anxiety or nervous excitement): 24 people, 63.16%
Confusion: 23 people, 60.53%
Confusional State: 20 people, 52.63%
Nausea And Vomiting: 19 people, 50.00%

What are the existing conditions these people have? *

Depression: 10 people, 26.32%
Stress And Anxiety: 4 people, 10.53%
Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 3 people, 7.89%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 7.89%
Parkinson's Disease: 2 people, 5.26%
Lower Respiratory Tract Infection: 2 people, 5.26%
Seasonal Allergy (allergic condition due to certain season): 1 person, 2.63%
Psychotic Disorder: 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Zimovane and have Insomnia exacerbated?

- Check whether Insomnia exacerbated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zimovane:

Zimovane (523 reports)

Browse all side effects of Zimovane:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia exacerbated:

Insomnia exacerbated (2,649 drugs)

Browse all the conditions that are associated with Insomnia exacerbated:

Insomnia exacerbated (974 conditions)

Related publications that referenced our studies

Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on eszopiclone (the active ingredients of Zimovane) and Zimovane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.