Zinacef and Coma - a phase IV clinical study of FDA data
Summary:
Coma is reported as a side effect among people who take Zinacef (cefuroxime sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Gentamicin, and have Nausea and vomiting.
The phase IV clinical study analyzes which people have Coma when taking Zinacef. It is created by eHealthMe based on reports of 1,789 people who have side effects when taking Zinacef from the FDA, and is updated regularly.
What is Zinacef?
Zinacef has active ingredients of cefuroxime sodium. eHealthMe is studying from 1,802 Zinacef users. Check the latest studies of Zinacef.
What is Coma?
Coma (state of unconsciousness lasting more than six hours) is found to be associated with 2,799 drugs and 3,207 conditions by eHealthMe. Check the latest studies of Coma.
1,789 people reported to have side effects when taking Zinacef.
Among them, 34 people (1.9%) have Coma.

Among these 34 people:
How long have people been on Zinacef when they have Coma? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Coma when taking Zinacef? *
- female: 41.18 %
- male: 58.82 %
What is the age of people who have Coma when taking Zinacef? *
- 0-1: 0.0 %
- 2-9: 6.67 %
- 10-19: 3.33 %
- 20-29: 0.0 %
- 30-39: 3.33 %
- 40-49: 16.67 %
- 50-59: 0.0 %
- 60+: 70.0 %
What are other drugs people take besides Zinacef? *
- Gentamicin: 7 people, 20.59%
- Lasix: 6 people, 17.65%
- Lopressor: 5 people, 14.71%
- Cellcept: 5 people, 14.71%
- Prograf: 4 people, 11.76%
- Solu-Medrol: 4 people, 11.76%
- Diflucan: 4 people, 11.76%
- Depakene: 4 people, 11.76%
- Cordarone: 4 people, 11.76%
- Phenytoin: 4 people, 11.76%
What are other side effects people have besides Coma? *
- Acute Kidney Failure: 6 people, 17.65%
- Depressed Level Of Consciousness: 6 people, 17.65%
- Loss Of Consciousness: 5 people, 14.71%
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 5 people, 14.71%
- Hypotension (abnormally low blood pressure): 5 people, 14.71%
- Respiratory Distress (difficulty in breathing): 4 people, 11.76%
- Cardiac Arrest: 4 people, 11.76%
- Blood Creatinine Increased: 4 people, 11.76%
- Muscle Contractions Involuntary (uncontrolled muscle contraction): 4 people, 11.76%
- Cerebral Oedema (swelling of brain): 4 people, 11.76%
What are the existing conditions these people have? *
- Tonsillitis (inflammation of tonsil): 2 people, 5.88%
- Nausea And Vomiting: 2 people, 5.88%
- Procedural Site Reaction: 1 person, 2.94%
- Post Procedural Pain: 1 person, 2.94%
- Personality Change: 1 person, 2.94%
- Bipolar Disorder (mood disorder): 1 person, 2.94%
* Approximation only. Some reports may have incomplete information.
Do you take Zinacef and have Coma?
- Check whether Coma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Zinacef:
- Zinacef (1,802 reports)
Coma treatments and more:
- Coma (57,420 reports)
How severe was Coma and when was it recovered:
Expand to all the drugs that have ingredients of cefuroxime sodium:
- Coma and drugs with ingredients of cefuroxime sodium (66 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zinacef:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Coma:
- Coma (2,799 drugs)
Browse all the conditions that are associated with Coma:
- Coma (3,207 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on cefuroxime sodium (the active ingredients of Zinacef) and Zinacef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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