Zinacef and Corneal opacity - a phase IV clinical study of FDA data

Summary:

Corneal opacity is reported as a side effect among people who take Zinacef (cefuroxime sodium), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Balanced Salt Solution, and have Eye infection.

The phase IV clinical study analyzes which people have Corneal opacity when taking Zinacef. It is created by eHealthMe based on reports of 1,789 people who have side effects when taking Zinacef from the FDA, and is updated regularly.

What is Zinacef?

Zinacef has active ingredients of cefuroxime sodium. eHealthMe is studying from 1,802 Zinacef users. Check the latest studies of Zinacef.

What is Corneal opacity?

Corneal opacity (scarring or clouding of the cornea) is found to be associated with 125 drugs and 317 conditions by eHealthMe. Check the latest studies of Corneal opacity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

1,789 people reported to have side effects when taking Zinacef.
Among them, 24 people (1.34%) have Corneal opacity.

Among these 24 people:

How long have people been on Zinacef when they have Corneal opacity? *

What is the gender of people who have Corneal opacity when taking Zinacef? *

female: 25 %
male: 75 %

What is the age of people who have Corneal opacity when taking Zinacef? *

What are other drugs people take besides Zinacef? *

Balanced Salt Solution: 1 person, 4.17%

What are other side effects people have besides Corneal opacity? *

Visual Disturbance: 9 people, 37.50%
Corneal Deposits: 5 people, 20.83%
Corneal Oedema (corneal swelling): 3 people, 12.50%
Visual Impairment: 2 people, 8.33%
Vision Blurred: 2 people, 8.33%
Visual Acuity Reduced (reduced clearness of vision): 1 person, 4.17%
Retinal Pigmentation (pigmentation of retina): 1 person, 4.17%
Ocular Toxicity (damages eye): 1 person, 4.17%
Corneal Disorder: 1 person, 4.17%
Corneal Defect (abnormality of cornea): 1 person, 4.17%

What are the existing conditions these people have? *

Eye Infection: 9 people, 37.50%

* Approximation only. Some reports may have incomplete information.

Do you take Zinacef and have Corneal opacity?

- Check whether Corneal opacity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zinacef:

Zinacef (1,802 reports)

Corneal opacity treatments and more:

Corneal opacity (1,595 reports)

Browse all side effects of Zinacef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Corneal opacity:

Corneal opacity (125 drugs)

Browse all the conditions that are associated with Corneal opacity:

Corneal opacity (317 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cefuroxime sodium (the active ingredients of Zinacef) and Zinacef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.