Zocor and Hepatocellular damage - a phase IV clinical study of FDA data

Summary:

Hepatocellular damage is reported as a side effect among people who take Zocor (simvastatin), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Lasix, and have Hyperlipidaemia.

The phase IV clinical study analyzes which people have Hepatocellular damage when taking Zocor. It is created by eHealthMe based on reports of 84,616 people who have side effects when taking Zocor from the FDA, and is updated regularly.

What is Zocor?

Zocor has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 86,545 Zocor users. Check the latest studies of Zocor.

What is Hepatocellular damage?

Hepatocellular damage (liver damage) is found to be associated with 503 drugs and 610 conditions by eHealthMe. Check the latest studies of Hepatocellular damage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

84,616 people reported to have side effects when taking Zocor.
Among them, 142 people (0.17%) have Hepatocellular damage.

Could Zocor cause Hepatocellular damage?

Among these 142 people:

How long have people been on Zocor when they have Hepatocellular damage? *

Click here to view more results

What is the gender of people who have Hepatocellular damage when taking Zocor? *

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* Approximation only. Some reports may have incomplete information.

Do you take Zocor and have Hepatocellular damage?

- Check whether Hepatocellular damage is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zocor:

Zocor (86,545 reports)

Hepatocellular damage treatments and more:

Hepatocellular damage (10,681 reports)

How severe was Hepatocellular damage and when was it recovered:

Hepatocellular damage in Zocor

Expand to all the drugs that have ingredients of simvastatin:

Hepatocellular damage and drugs with ingredients of simvastatin (183 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zocor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatocellular damage:

Hepatocellular damage (503 drugs)

Browse all the conditions that are associated with Hepatocellular damage:

Hepatocellular damage (610 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin (the active ingredients of Zocor) and Zocor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.