Zofran and Haemolysis - a phase IV clinical study of FDA data

Summary:

Haemolysis is reported as a side effect among people who take Zofran (ondansetron hydrochloride), especially for people who are male, 50-59 old, also take Tylenol, and have Paroxysmal nocturnal haemoglobinuria.

The phase IV clinical study analyzes which people have Haemolysis when taking Zofran. It is created by eHealthMe based on reports of 93,713 people who have side effects when taking Zofran from the FDA, and is updated regularly.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

What is Haemolysis?

Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid) is found to be associated with 611 drugs and 837 conditions by eHealthMe. Check the latest studies of Haemolysis.

On Jul, 26, 2026

93,713 people reported to have side effects when taking Zofran.
Among them, 67 people (0.07%) have Haemolysis.

Among these 67 people:

What is the gender of people who have Haemolysis when taking Zofran? *

female: 41.27 %
male: 58.73 %

What is the age of people who have Haemolysis when taking Zofran? *

What are other drugs people take besides Zofran? *

What are other side effects people have besides Haemolysis? *

Thrombocytopenia (decrease of platelets in blood): 16 people, 23.88%
Acute Kidney Failure: 14 people, 20.90%
Hepatic Failure (liver failure): 14 people, 20.90%
Haemoglobin Decreased: 12 people, 17.91%
Blood Bilirubin Increased: 12 people, 17.91%
Gallstones (stone formation by bile component): 10 people, 14.93%
Fatigue (feeling of tiredness): 10 people, 14.93%
Septic Shock (shock due to blood infection): 10 people, 14.93%
Encephalopathy (functioning of the brain is affected by some agent or condition): 10 people, 14.93%
Cardiac Failure Congestive: 10 people, 14.93%

What are the existing conditions these people have? *

Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 13 people, 19.40%
Pain: 7 people, 10.45%
Fungal Endocarditis (fungal infection of the inner layer of the heart): 3 people, 4.48%
Breast Cancer: 3 people, 4.48%
Ovarian Cancer (cancer of ovary): 3 people, 4.48%
Oesophageal Candidiasis (fungal infection of oesophagus): 3 people, 4.48%
Diarrhea: 3 people, 4.48%
Diffuse Large B-Cell Lymphoma Stage Iii (cancer of b cells, a type of white blood cell-stage iii): 2 people, 2.99%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 2 people, 2.99%
High Blood Pressure: 2 people, 2.99%

* Approximation only. Some reports may have incomplete information.

Do you take Zofran and have Haemolysis?

- Check whether Haemolysis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zofran:

Zofran (94,987 reports)

Haemolysis treatments and more:

Haemolysis (9,155 reports)

Browse all side effects of Zofran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemolysis:

Haemolysis (611 drugs)

Browse all the conditions that are associated with Haemolysis:

Haemolysis (837 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ondansetron hydrochloride (the active ingredients of Zofran) and Zofran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.