Zofran and Infrequent bowel movements - a phase IV clinical study of FDA data

Summary:

Infrequent bowel movements is reported as a side effect among people who take Zofran (ondansetron hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Percocet, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Infrequent bowel movements when taking Zofran. It is created by eHealthMe based on reports of 93,713 people who have side effects when taking Zofran from the FDA, and is updated regularly.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

What is Infrequent bowel movements?

Infrequent bowel movements is found to be associated with 321 drugs and 450 conditions by eHealthMe. Check the latest studies of Infrequent bowel movements.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

93,713 people reported to have side effects when taking Zofran.
Among them, 30 people (0.03%) have Infrequent bowel movements.

Could Zofran cause Infrequent bowel movements?

Among these 30 people:

How long have people been on Zofran when they have Infrequent bowel movements? *

What is the gender of people who have Infrequent bowel movements when taking Zofran? *

female: 55.17 %
male: 44.83 %

What is the age of people who have Infrequent bowel movements when taking Zofran? *

What are other drugs people take besides Zofran? *

What are other side effects people have besides Infrequent bowel movements? *

Constipation: 12 people, 40.00%
Diarrhea: 11 people, 36.67%
Joint Pain: 10 people, 33.33%
Dizziness: 9 people, 30.00%
Muscle Aches (muscle pain): 8 people, 26.67%
Headache (pain in head): 8 people, 26.67%
Pain: 8 people, 26.67%
Cough: 7 people, 23.33%
Weakness: 7 people, 23.33%
Migraine (headache): 7 people, 23.33%

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 20.00%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 4 people, 13.33%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 2 people, 6.67%
Stress And Anxiety: 2 people, 6.67%
Pain: 2 people, 6.67%
Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 2 people, 6.67%
Diabetes: 2 people, 6.67%
Dizziness: 1 person, 3.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.33%
Flatulence (flatus expelled through the anus): 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Zofran and have Infrequent bowel movements?

- Check whether Infrequent bowel movements is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zofran:

Zofran (94,987 reports)

Browse all side effects of Zofran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Infrequent bowel movements:

Infrequent bowel movements (321 drugs)

Browse all the conditions that are associated with Infrequent bowel movements:

Infrequent bowel movements (450 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ondansetron hydrochloride (the active ingredients of Zofran) and Zofran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.