Zofran and Microcytic anaemia - a phase IV clinical study of FDA data

Summary:

Microcytic anaemia is reported as a side effect among people who take Zofran (ondansetron hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Microcytic anaemia when taking Zofran. It is created by eHealthMe based on reports of 93,713 people who have side effects when taking Zofran from the FDA, and is updated regularly.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

What is Microcytic anaemia?

Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells) is found to be associated with 409 drugs and 508 conditions by eHealthMe. Check the latest studies of Microcytic anaemia.



On Jul, 15, 2026

93,713 people reported to have side effects when taking Zofran.
Among them, 50 people (0.05%) have Microcytic anaemia.

Could Zofran cause Microcytic anaemia?

Among these 50 people:

How long have people been on Zofran when they have Microcytic anaemia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Microcytic anaemia when taking Zofran? *

  • female: 70.73 %
  • male: 29.27 %

What is the age of people who have Microcytic anaemia when taking Zofran? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.7 %
  • 30-39: 2.7 %
  • 40-49: 24.32 %
  • 50-59: 35.14 %
  • 60+: 35.14 %

What are other drugs people take besides Zofran? *

  1. Zometa: 21 people, 42.00%
  2. Protonix: 20 people, 40.00%
  3. Reglan: 19 people, 38.00%
  4. Diovan: 16 people, 32.00%
  5. Lantus: 16 people, 32.00%
  6. Paxil: 16 people, 32.00%
  7. Ultram: 16 people, 32.00%
  8. Oxycontin: 16 people, 32.00%
  9. Arimidex: 15 people, 30.00%
  10. Dilaudid: 14 people, 28.00%

What are other side effects people have besides Microcytic anaemia? *

  1. Dyspnea (difficult or laboured breathing): 31 people, 62.00%
  2. Abdominal Pain: 30 people, 60.00%
  3. Fever: 30 people, 60.00%
  4. Hypokalemia (low potassium): 28 people, 56.00%
  5. Iron Deficiency Anaemia: 27 people, 54.00%
  6. Constipation: 25 people, 50.00%
  7. Atelectasis (partial or complete collapse of the lung): 24 people, 48.00%
  8. Back Pain: 24 people, 48.00%
  9. Dehydration (dryness resulting from the removal of water): 23 people, 46.00%
  10. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 22 people, 44.00%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 19 people, 38.00%
  2. High Blood Pressure: 15 people, 30.00%
  3. Breast Cancer: 15 people, 30.00%
  4. Depression: 14 people, 28.00%
  5. Diabetes: 14 people, 28.00%
  6. Bone Pain: 14 people, 28.00%
  7. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 10.00%
  8. Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 4 people, 8.00%
  9. Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 3 people, 6.00%
  10. Pain: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Zofran and have Microcytic anaemia?

- Check whether Microcytic anaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zofran:

Microcytic anaemia treatments and more:

How severe was Microcytic anaemia and when was it recovered:

Expand to all the drugs that have ingredients of ondansetron hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zofran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Microcytic anaemia:

Browse all the conditions that are associated with Microcytic anaemia:


How the study uses the data?

The study uses data from the FDA. It is based on ondansetron hydrochloride (the active ingredients of Zofran) and Zofran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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