Zoledronic and Cardiotoxicity - a phase IV clinical study of FDA data

Summary:

Cardiotoxicity is reported as a side effect among people who take Zoledronic (zoledronic acid), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Ondansetron, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Cardiotoxicity when taking Zoledronic. It is created by eHealthMe based on reports of 29,760 people who have side effects when taking Zoledronic from the FDA, and is updated regularly.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

What is Cardiotoxicity?

Cardiotoxicity (damage to the heart muscle) is found to be associated with 385 drugs and 511 conditions by eHealthMe. Check the latest studies of Cardiotoxicity.

On Aug, 02, 2026

29,760 people reported to have side effects when taking Zoledronic.
Among them, 21 people (0.07%) have Cardiotoxicity.

Among these 21 people:

How long have people been on Zoledronic when they have Cardiotoxicity? *

What is the gender of people who have Cardiotoxicity when taking Zoledronic? *

female: 65 %
male: 35 %

What is the age of people who have Cardiotoxicity when taking Zoledronic? *

What are other drugs people take besides Zoledronic? *

Tamiflu: 4 people, 19.05%
Morphine: 4 people, 19.05%
Ondansetron: 4 people, 19.05%
Zytiga: 2 people, 9.52%
Piperacillin And Tazobactam: 2 people, 9.52%
Heparin: 2 people, 9.52%
Docetaxel: 1 person, 4.76%
Cyclophosphamide: 1 person, 4.76%
Doxil: 1 person, 4.76%
Herceptin: 1 person, 4.76%

What are other side effects people have besides Cardiotoxicity? *

High Blood Pressure: 4 people, 19.05%
Pain: 4 people, 19.05%
Fatigue (feeling of tiredness): 3 people, 14.29%
Nausea (feeling of having an urge to vomit): 3 people, 14.29%
Nausea And Vomiting: 3 people, 14.29%
Neuropathy Peripheral (surface nerve damage): 3 people, 14.29%
Dyspnea (difficult or laboured breathing): 3 people, 14.29%
Left Ventricular Dysfunction: 2 people, 9.52%
Impaired Healing: 2 people, 9.52%
Hot Flush (sudden feelings of heat): 2 people, 9.52%

What are the existing conditions these people have? *

Breast Cancer Metastatic: 4 people, 19.05%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 19.05%
Spindle Cell Sarcoma (a type of connective tissue cancer in which the cells): 2 people, 9.52%
Prostate Cancer Metastatic: 2 people, 9.52%
Multiple Myeloma (cancer of the plasma cells): 2 people, 9.52%
Metastases To Bone (cancer spreads to bone): 2 people, 9.52%
Inflammatory Myofibroblastic Tumor: 2 people, 9.52%
Connective Tissue Neoplasm (tumour of connective tissue): 2 people, 9.52%
Breast Cancer: 2 people, 9.52%
Nausea And Vomiting: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Zoledronic and have Cardiotoxicity?

- Check whether Cardiotoxicity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoledronic:

Zoledronic (29,812 reports)

Cardiotoxicity treatments and more:

Cardiotoxicity (8,120 reports)

Browse all side effects of Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiotoxicity:

Cardiotoxicity (385 drugs)

Browse all the conditions that are associated with Cardiotoxicity:

Cardiotoxicity (511 conditions)

Related publications that referenced our studies

Alam, S., Illo, C., Ma, Y. T., & Punia, P. , "Gemcitabine-induced cardiotoxicity in patients receiving adjuvant chemotherapy for pancreatic cancer: a case series", Case reports in oncology, 2018 Jan .
Alam, S., Illo, C., Ma, Y. T., & Punia, P. , "Gemcitabine-induced cardiotoxicity in patients receiving adjuvant chemotherapy for pancreatic cancer: a case series", Case reports in oncology, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid (the active ingredients of Zoledronic) and Zoledronic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.