Zoledronic and Hypothermia - a phase IV clinical study of FDA data

Summary:

Hypothermia is reported as a side effect among people who take Zoledronic (zoledronic acid), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Glimepiride, and have Osteoporosis.

The phase IV clinical study analyzes which people have Hypothermia when taking Zoledronic. It is created by eHealthMe based on reports of 29,760 people who have side effects when taking Zoledronic from the FDA, and is updated regularly.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

What is Hypothermia?

Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions) is found to be associated with 775 drugs and 997 conditions by eHealthMe. Check the latest studies of Hypothermia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 30, 2026

29,760 people reported to have side effects when taking Zoledronic.
Among them, 11 people (0.04%) have Hypothermia.

Could Zoledronic cause Hypothermia?

Among these 11 people:

How long have people been on Zoledronic when they have Hypothermia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypothermia when taking Zoledronic? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Hypothermia when taking Zoledronic? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Zoledronic? *

  1. Indapamide: 5 people, 45.45%
  2. Nateglinide: 5 people, 45.45%
  3. Ergocalciferol: 5 people, 45.45%
  4. Furosemide: 5 people, 45.45%
  5. Glimepiride: 5 people, 45.45%
  6. Metoprolol Tartrate: 3 people, 27.27%
  7. Risedronate Sodium: 2 people, 18.18%
  8. Metformin: 2 people, 18.18%
  9. Herceptin: 1 person, 9.09%
  10. Aspirin: 1 person, 9.09%

What are other side effects people have besides Hypothermia? *

  1. Hypotension (abnormally low blood pressure): 7 people, 63.64%
  2. Heart Rate Decreased: 6 people, 54.55%
  3. Unresponsive To Stimuli: 6 people, 54.55%
  4. Dry Skin: 5 people, 45.45%
  5. Pupillary Reflex Impaired: 5 people, 45.45%
  6. Lactic Acidosis (low ph in body tissues): 5 people, 45.45%
  7. Oedema Peripheral (superficial swelling): 5 people, 45.45%
  8. Drug Level Increased: 4 people, 36.36%
  9. Respiratory Rate Decreased (less breathing rate/min): 4 people, 36.36%
  10. Hyperkalemia (damage to or disease of the kidney): 4 people, 36.36%

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 7 people, 63.64%
  2. Type 2 Diabetes: 5 people, 45.45%
  3. Stable Angina (a constant chest pain): 1 person, 9.09%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
  5. Oral Candidiasis (fungal infection of mouth): 1 person, 9.09%
  6. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 1 person, 9.09%
  7. Metastases To Bone (cancer spreads to bone): 1 person, 9.09%
  8. High Blood Pressure: 1 person, 9.09%
  9. High Blood Cholesterol: 1 person, 9.09%
  10. Haemoglobin Decreased: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Zoledronic and have Hypothermia?

- Check whether Hypothermia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoledronic:

Hypothermia treatments and more:

How severe was Hypothermia and when was it recovered:

Expand to all the drugs that have ingredients of zoledronic acid:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothermia:

Browse all the conditions that are associated with Hypothermia:


How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid (the active ingredients of Zoledronic) and Zoledronic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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