Zoledronic and Multiple fractures - a phase IV clinical study of FDA data

Summary:

Multiple fractures is reported as a side effect among people who take Zoledronic (zoledronic acid), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prolia, and have Osteoporosis.

The phase IV clinical study analyzes which people have Multiple fractures when taking Zoledronic. It is created by eHealthMe based on reports of 29,760 people who have side effects when taking Zoledronic from the FDA, and is updated regularly.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

What is Multiple fractures?

Multiple fractures is found to be associated with 729 drugs and 727 conditions by eHealthMe. Check the latest studies of Multiple fractures.

On Aug, 08, 2026

29,760 people reported to have side effects when taking Zoledronic.
Among them, 21 people (0.07%) have Multiple fractures.

$Could Zoledronic cause Multiple fractures?$

Among these 21 people:

How long have people been on Zoledronic when they have Multiple fractures? *

What is the gender of people who have Multiple fractures when taking Zoledronic? *

female: 62.5 %
male: 37.5 %

What is the age of people who have Multiple fractures when taking Zoledronic? *

What are other drugs people take besides Zoledronic? *

What are other side effects people have besides Multiple fractures? *

Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 5 people, 23.81%
Osteomalacia (softening of the bones due to a lack of vitamin d): 4 people, 19.05%
Back Pain: 3 people, 14.29%
Drug Ineffective: 3 people, 14.29%
Osteoporosis (bones weak and more likely to break): 3 people, 14.29%
Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 14.29%
Joint Pain: 2 people, 9.52%
Blood Creatinine Increased: 2 people, 9.52%
Callus Formation Delayed: 2 people, 9.52%
Fanconi Syndrome Acquired (self developed genetic disease of kidney damage due to defective transport system): 2 people, 9.52%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 11 people, 52.38%
Paget's Disease (disorder that involves abnormal bone destruction and regrowth, which results in deformity): 3 people, 14.29%
Breast Cancer: 2 people, 9.52%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.76%
Multiple Myeloma (cancer of the plasma cells): 1 person, 4.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Zoledronic and have Multiple fractures?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoledronic:

Zoledronic (29,812 reports)

Browse all side effects of Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Multiple fractures:

Multiple fractures (729 drugs)

Browse all the conditions that are associated with Multiple fractures:

Multiple fractures (727 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid (the active ingredients of Zoledronic) and Zoledronic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.