Zoloft and Foetal death - a phase IV clinical study of FDA data

Summary:

Foetal death is reported as a side effect among people who take Zoloft (sertraline hydrochloride), especially for people who are female, 30-39 old, have been taking the drug for 1 - 6 months also take Zofran, and have Birth control.

The study is created by eHealthMe based on reports of 128,159 people who have side effects when taking Zoloft from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

On Jul, 07, 2026

128,159 people reported to have side effects when taking Zoloft.
Among them, 17 people (0.01%) died.

Among these 17 people:

How long have people been on Zoloft when they died? *

What is the gender of people who died when taking Zoloft? *

female: 100 %
male: 0.0 %

What is the age of people who died when taking Zoloft? *

What are other drugs people take besides Zoloft? *

What are other side effects people have before they died? *

Maternal Exposure During Pregnancy (use of substance during pregnancy): 3 people, 17.65%
Intra-Abdominal Haemorrhage (intra-abdominal bleeding): 2 people, 11.76%
Placenta Abruptio: 2 people, 11.76%
Twin Pregnancy (two babies in uterus): 2 people, 11.76%
Abnormal Behavior: 2 people, 11.76%
Abortion Spontaneous (naturally occurring miscarriage): 2 people, 11.76%
Bradycardia Foetal (abnormally slow fetal heart rate, usually below 100 beats/min): 2 people, 11.76%
Hot Flush (sudden feelings of heat): 1 person, 5.88%
Homicidal Ideation (thoughts about human killing another human): 1 person, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 3 people, 17.65%
Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood): 3 people, 17.65%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 3 people, 17.65%
Blood Potassium Decreased: 3 people, 17.65%
Birth Control: 3 people, 17.65%
Psychotic Disorder: 2 people, 11.76%
Bipolar Disorder (mood disorder): 2 people, 11.76%
Appendicitis (inflammation of the appendix): 2 people, 11.76%
Sleep Disorder: 1 person, 5.88%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoloft:

Zoloft (138,798 reports)

Expand to all the drugs that have ingredients of sertraline hydrochloride:

Foetal death and drugs with ingredients of sertraline hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Foetal death:

Foetal death (295 drugs)

Browse all the conditions that are associated with Foetal death:

Foetal death (315 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Zoloft) and Zoloft (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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