Zolpidem and Febrile bone marrow aplasia - a phase IV clinical study of FDA data

Summary:

Febrile bone marrow aplasia is reported as a side effect among people who take Zolpidem (zolpidem tartrate), especially for people who are female, 60+ old, also take Sodium Bicarbonate, and have Tonsillar neoplasm.

The phase IV clinical study analyzes which people have Febrile bone marrow aplasia when taking Zolpidem. It is created by eHealthMe based on reports of 90,339 people who have side effects when taking Zolpidem from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

What is Febrile bone marrow aplasia?

Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells) is found to be associated with 294 drugs and 465 conditions by eHealthMe. Check the latest studies of Febrile bone marrow aplasia.

On Jul, 31, 2026

90,339 people reported to have side effects when taking Zolpidem.
Among them, 27 people (0.03%) have Febrile bone marrow aplasia.

Could Zolpidem cause Febrile bone marrow aplasia?

Among these 27 people:

What is the gender of people who have Febrile bone marrow aplasia when taking Zolpidem? *

female: 65.38 %
male: 34.62 %

What is the age of people who have Febrile bone marrow aplasia when taking Zolpidem? *

What are other drugs people take besides Zolpidem? *

What are other side effects people have besides Febrile bone marrow aplasia? *

Acute Kidney Failure: 6 people, 22.22%
General Physical Health Deterioration (weak health status): 5 people, 18.52%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 4 people, 14.81%
Urinary Tract Infection: 4 people, 14.81%
Blood Phosphorus Decreased: 4 people, 14.81%
Hypokalemia (low potassium): 4 people, 14.81%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 4 people, 14.81%
Shock Haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding): 3 people, 11.11%
Anaemia (lack of blood): 3 people, 11.11%
Dehydration (dryness resulting from the removal of water): 3 people, 11.11%

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 14.81%
Pain: 4 people, 14.81%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 14.81%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 14.81%
Tonsillar Neoplasm (cancer or tumour of tonsil): 4 people, 14.81%
Infection: 3 people, 11.11%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 11.11%
Breast Cancer: 3 people, 11.11%
Burkitt Lymphoma (cancer of the lymphatic system): 3 people, 11.11%
Endocarditis (inflammation in heart muscle): 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Zolpidem and have Febrile bone marrow aplasia?

- Check whether Febrile bone marrow aplasia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zolpidem:

Zolpidem (92,695 reports)

Browse all side effects of Zolpidem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Febrile bone marrow aplasia:

Febrile bone marrow aplasia (294 drugs)

Browse all the conditions that are associated with Febrile bone marrow aplasia:

Febrile bone marrow aplasia (465 conditions)

Related publications that referenced our studies

Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Zolpidem) and Zolpidem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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