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Zolpidem and Hydrocephalus - a phase IV clinical study of FDA data

Summary:

Hydrocephalus is reported as a side effect among people who take Zolpidem (zolpidem tartrate), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Metoclopramide, and have High blood pressure.

The phase IV clinical study analyzes which people have Hydrocephalus when taking Zolpidem. It is created by eHealthMe based on reports of 90,339 people who have side effects when taking Zolpidem from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

What is Hydrocephalus?

Hydrocephalus (water on the brain) is found to be associated with 755 drugs and 1,370 conditions by eHealthMe. Check the latest studies of Hydrocephalus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 04, 2026

90,339 people reported to have side effects when taking Zolpidem.
Among them, 37 people (0.04%) have Hydrocephalus.

Could Zolpidem cause Hydrocephalus?

Among these 37 people:

How long have people been on Zolpidem when they have Hydrocephalus? *

  • < 1 month: 25.0 %
  • 1 - 6 months: 12.5 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 62.5 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hydrocephalus when taking Zolpidem? *

  • female: 38.89 %
  • male: 61.11 %

What is the age of people who have Hydrocephalus when taking Zolpidem? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 14.29 %
  • 20-29: 2.86 %
  • 30-39: 0.0 %
  • 40-49: 14.29 %
  • 50-59: 17.14 %
  • 60+: 51.43 %

What are other drugs people take besides Zolpidem? *

  1. Acetaminophen: 8 people, 21.62%
  2. Amlodipine: 8 people, 21.62%
  3. Metoclopramide: 8 people, 21.62%
  4. Lisinopril: 6 people, 16.22%
  5. Methotrexate: 6 people, 16.22%
  6. Acyclovir: 6 people, 16.22%
  7. Docetaxel: 5 people, 13.51%
  8. Dapsone: 5 people, 13.51%
  9. Mesna: 5 people, 13.51%
  10. Magnesium Sulfate: 5 people, 13.51%

What are other side effects people have besides Hydrocephalus? *

  1. Pleural Effusion (water on the lungs): 14 people, 37.84%
  2. Headache (pain in head): 11 people, 29.73%
  3. Thrombocytopenia (decrease of platelets in blood): 11 people, 29.73%
  4. Pain: 9 people, 24.32%
  5. Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 9 people, 24.32%
  6. Blood Alkaline Phosphatase Increased: 9 people, 24.32%
  7. Dyspnea (difficult or laboured breathing): 9 people, 24.32%
  8. Fever: 8 people, 21.62%
  9. Fall: 8 people, 21.62%
  10. Depressed Level Of Consciousness: 8 people, 21.62%

What are the existing conditions these people have? *

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 13.51%
  2. Stress And Anxiety: 5 people, 13.51%
  3. Prostate Cancer: 5 people, 13.51%
  4. High Blood Pressure: 5 people, 13.51%
  5. Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 4 people, 10.81%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 8.11%
  7. Pain: 3 people, 8.11%
  8. Hepatitis C: 3 people, 8.11%
  9. Cerebellar Infarction (impaired blood circulation to cerebellum): 2 people, 5.41%
  10. Diabetes: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Zolpidem and have Hydrocephalus?

- Check whether Hydrocephalus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zolpidem:

Hydrocephalus treatments and more:

How severe was Hydrocephalus and when was it recovered:

Expand to all the drugs that have ingredients of zolpidem tartrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zolpidem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hydrocephalus:

Browse all the conditions that are associated with Hydrocephalus:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Zolpidem) and Zolpidem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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