Zolpidem and Hyperphosphataemia - a phase IV clinical study of FDA data

Summary:

Hyperphosphataemia is reported as a side effect among people who take Zolpidem (zolpidem tartrate), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Nexium, and have Chronic kidney disease.

The phase IV clinical study analyzes which people have Hyperphosphataemia when taking Zolpidem. It is created by eHealthMe based on reports of 90,339 people who have side effects when taking Zolpidem from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,696 Zolpidem users. Check the latest studies of Zolpidem.

What is Hyperphosphataemia?

Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood) is found to be associated with 429 drugs and 377 conditions by eHealthMe. Check the latest studies of Hyperphosphataemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

90,339 people reported to have side effects when taking Zolpidem.
Among them, 21 people (0.02%) have Hyperphosphataemia.

Could Zolpidem cause Hyperphosphataemia?

Among these 21 people:

How long have people been on Zolpidem when they have Hyperphosphataemia? *

What is the gender of people who have Hyperphosphataemia when taking Zolpidem? *

female: 47.62 %
male: 52.38 %

What is the age of people who have Hyperphosphataemia when taking Zolpidem? *

What are other drugs people take besides Zolpidem? *

What are other side effects people have besides Hyperphosphataemia? *

Acute Kidney Failure: 5 people, 23.81%
Chronic Kidney Disease: 4 people, 19.05%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 4 people, 19.05%
Nephrogenic Anaemia (anaemia due to kidney disease): 4 people, 19.05%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 19.05%
Weakness: 3 people, 14.29%
Fall: 3 people, 14.29%
Consciousness - Decreased: 3 people, 14.29%
Nausea (feeling of having an urge to vomit): 3 people, 14.29%
Renal Injury (kidney injury): 3 people, 14.29%

What are the existing conditions these people have? *

Chronic Kidney Disease: 4 people, 19.05%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 14.29%
High Blood Cholesterol: 2 people, 9.52%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 9.52%
Pain: 2 people, 9.52%
Ocular Discomfort (a generic expression when there is lack of ease in/about the eyes): 2 people, 9.52%
Cystinosis (abnormal accumulation of the amino acid cystine): 2 people, 9.52%
Diabetes: 2 people, 9.52%
Vitamin D Abnormal: 1 person, 4.76%
Blood Magnesium Abnormal: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Zolpidem and have Hyperphosphataemia?

- Check whether Hyperphosphataemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zolpidem:

Zolpidem (92,696 reports)

Browse all side effects of Zolpidem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperphosphataemia:

Hyperphosphataemia (429 drugs)

Browse all the conditions that are associated with Hyperphosphataemia:

Hyperphosphataemia (377 conditions)

Related publications that referenced our studies

Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Zolpidem) and Zolpidem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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