Zolpidem and Onychoclasis - a phase IV clinical study of FDA data

Summary:

Onychoclasis is reported as a side effect among people who take Zolpidem (zolpidem tartrate), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Vitamin D3, and have High blood pressure.

The phase IV clinical study analyzes which people have Onychoclasis when taking Zolpidem. It is created by eHealthMe based on reports of 90,339 people who have side effects when taking Zolpidem from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

What is Onychoclasis?

Onychoclasis (breaking of the nails) is found to be associated with 614 drugs and 607 conditions by eHealthMe. Check the latest studies of Onychoclasis.

On Aug, 08, 2026

90,339 people reported to have side effects when taking Zolpidem.
Among them, 40 people (0.04%) have Onychoclasis.

Among these 40 people:

How long have people been on Zolpidem when they have Onychoclasis? *

What is the gender of people who have Onychoclasis when taking Zolpidem? *

female: 82.35 %
male: 17.65 %

What is the age of people who have Onychoclasis when taking Zolpidem? *

What are other drugs people take besides Zolpidem? *

What are other side effects people have besides Onychoclasis? *

Hair Loss: 14 people, 35.00%
Fatigue (feeling of tiredness): 12 people, 30.00%
Dizziness: 9 people, 22.50%
Dry Mouth: 9 people, 22.50%
Headache (pain in head): 8 people, 20.00%
Weakness: 8 people, 20.00%
Pain In Extremity: 8 people, 20.00%
Diarrhea: 8 people, 20.00%
Joint Pain: 8 people, 20.00%
Weight Increased: 7 people, 17.50%

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 15.00%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 10.00%
Depression: 4 people, 10.00%
Stress And Anxiety: 3 people, 7.50%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.50%
Breast Cancer Female: 3 people, 7.50%
Pain: 3 people, 7.50%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 7.50%
Lung Carcinoma Cell Type Unspecified Stage 0 (the lung cancer has not spread beyond the inner lining of the lung): 2 people, 5.00%
Birth Control: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Zolpidem and have Onychoclasis?

- Check whether Onychoclasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zolpidem:

Zolpidem (92,695 reports)

Onychoclasis treatments and more:

Onychoclasis (7,925 reports)

Browse all side effects of Zolpidem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Onychoclasis:

Onychoclasis (614 drugs)

Browse all the conditions that are associated with Onychoclasis:

Onychoclasis (607 conditions)

Related publications that referenced our studies

Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Zolpidem) and Zolpidem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.