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Zolpidem and Systemic sclerosis (scleroderma) - a phase IV clinical study of FDA data

Summary:

Systemic sclerosis (scleroderma) is reported as a side effect among people who take Zolpidem (zolpidem tartrate), especially for people who are female, 60+ old, also take Plavix, and have High blood pressure.

The phase IV clinical study analyzes which people have Systemic sclerosis (scleroderma) when taking Zolpidem. It is created by eHealthMe based on reports of 90,339 people who have side effects when taking Zolpidem from the FDA, and is updated regularly.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

What is Systemic sclerosis (scleroderma)?

Systemic sclerosis (scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin) is found to be associated with 493 drugs and 857 conditions by eHealthMe. Check the latest studies of Systemic sclerosis (scleroderma).

On Jul, 26, 2026

90,339 people reported to have side effects when taking Zolpidem.
Among them, 21 people (0.02%) have Systemic sclerosis (scleroderma).

Could Zolpidem cause Systemic sclerosis (scleroderma)?

Among these 21 people:

What is the gender of people who have Systemic sclerosis (scleroderma) when taking Zolpidem? *

  • female: 52.94 %
  • male: 47.06 %

What is the age of people who have Systemic sclerosis (scleroderma) when taking Zolpidem? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.67 %
  • 30-39: 0.0 %
  • 40-49: 6.67 %
  • 50-59: 6.67 %
  • 60+: 80.0 %

What are other drugs people take besides Zolpidem? *

  1. Plavix: 8 people, 38.10%
  2. Prilosec: 7 people, 33.33%
  3. Metformin: 7 people, 33.33%
  4. Prednisone: 7 people, 33.33%
  5. Tamsulosin: 7 people, 33.33%
  6. Ativan: 6 people, 28.57%
  7. Vicodin: 6 people, 28.57%
  8. Solu-Medrol: 6 people, 28.57%
  9. Lisinopril: 6 people, 28.57%
  10. Procardia Xl: 6 people, 28.57%

What are other side effects people have besides Systemic sclerosis (scleroderma)? *

  1. Thrombocytopenia (decrease of platelets in blood): 6 people, 28.57%
  2. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 5 people, 23.81%
  3. Vaginal Bleeding: 5 people, 23.81%
  4. Therapeutic Response Decreased (less preventive response): 5 people, 23.81%
  5. Viith Nerve Paralysis: 4 people, 19.05%
  6. Embolism Venous (embolus may pass into the arterial system): 3 people, 14.29%
  7. Weight Increased: 2 people, 9.52%
  8. Swelling: 2 people, 9.52%
  9. Diarrhea: 2 people, 9.52%
  10. Pleural Effusion (water on the lungs): 2 people, 9.52%

What are the existing conditions these people have? *

  1. High Blood Pressure: 9 people, 42.86%
  2. Bladder Transitional Cell Carcinoma (types of bladder cancer): 7 people, 33.33%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 33.33%
  4. Prostatomegaly (enlargement of the prostate): 7 people, 33.33%
  5. Diabetes: 7 people, 33.33%
  6. Dyslipidaemia (abnormal amount of lipids): 7 people, 33.33%
  7. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 7 people, 33.33%
  8. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 7 people, 33.33%
  9. Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 5 people, 23.81%
  10. Nausea (feeling of having an urge to vomit): 5 people, 23.81%

* Approximation only. Some reports may have incomplete information.

Do you take Zolpidem and have Systemic sclerosis (scleroderma)?

- Check whether Systemic sclerosis (scleroderma) is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zolpidem:

Systemic sclerosis (scleroderma) treatments and more:

How severe was Systemic sclerosis (scleroderma) and when was it recovered:

Expand to all the drugs that have ingredients of zolpidem tartrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zolpidem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systemic sclerosis (scleroderma):

Browse all the conditions that are associated with Systemic sclerosis (scleroderma):

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on zolpidem tartrate (the active ingredients of Zolpidem) and Zolpidem (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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