Zomig and Intervertebral disc protrusion - a phase IV clinical study of FDA data

Summary:

Intervertebral disc protrusion is reported as a side effect among people who take Zomig (zolmitriptan), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Neurontin, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Intervertebral disc protrusion when taking Zomig. It is created by eHealthMe based on reports of 6,908 people who have side effects when taking Zomig from the FDA, and is updated regularly.

What is Zomig?

Zomig has active ingredients of zolmitriptan. It is often used in migraine. eHealthMe is studying from 7,356 Zomig users. Check the latest studies of Zomig.

What is Intervertebral disc protrusion?

Intervertebral disc protrusion (spinal disc protrusion) is found to be associated with 1,531 drugs and 1,306 conditions by eHealthMe. Check the latest studies of Intervertebral disc protrusion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

6,908 people reported to have side effects when taking Zomig.
Among them, 23 people (0.33%) have Intervertebral disc protrusion.

Could Zomig cause Intervertebral disc protrusion?

Among these 23 people:

How long have people been on Zomig when they have Intervertebral disc protrusion? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 25 %
  • 5 - 10 years: 75 %
  • 10+ years: 0.0 %

What is the gender of people who have Intervertebral disc protrusion when taking Zomig? *

  • female: 89.47 %
  • male: 10.53 %

What is the age of people who have Intervertebral disc protrusion when taking Zomig? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 10 %
  • 40-49: 20 %
  • 50-59: 40 %
  • 60+: 30 %

What are other drugs people take besides Zomig? *

  1. Neurontin: 12 people, 52.17%
  2. Topamax: 8 people, 34.78%
  3. Cymbalta: 8 people, 34.78%
  4. Vitamin D: 6 people, 26.09%
  5. Pantoprazole: 5 people, 21.74%
  6. Amlodipine: 5 people, 21.74%
  7. Clopidogrel: 5 people, 21.74%
  8. Arava: 5 people, 21.74%
  9. Promethazine: 4 people, 17.39%
  10. Calcium: 4 people, 17.39%

What are other side effects people have besides Intervertebral disc protrusion? *

  1. Headache (pain in head): 9 people, 39.13%
  2. Back Pain: 7 people, 30.43%
  3. Joint Pain: 7 people, 30.43%
  4. Sleep Apnea Syndrome: 7 people, 30.43%
  5. Fatigue (feeling of tiredness): 6 people, 26.09%
  6. Hypotension (abnormally low blood pressure): 6 people, 26.09%
  7. High Blood Pressure: 6 people, 26.09%
  8. Heart Rate Decreased: 6 people, 26.09%
  9. Weight Decreased: 5 people, 21.74%
  10. Infusion Related Reaction: 5 people, 21.74%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 26.09%
  2. Pain: 5 people, 21.74%
  3. Insomnia (sleeplessness): 4 people, 17.39%
  4. Stress And Anxiety: 3 people, 13.04%
  5. High Blood Pressure: 3 people, 13.04%
  6. Multiple Myeloma (cancer of the plasma cells): 2 people, 8.70%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.70%
  8. Osteoporosis (bones weak and more likely to break): 2 people, 8.70%
  9. Psoriasis (immune-mediated disease that affects the skin): 2 people, 8.70%
  10. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Zomig and have Intervertebral disc protrusion?

- Check whether Intervertebral disc protrusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zomig:

Intervertebral disc protrusion treatments and more:

How severe was Intervertebral disc protrusion and when was it recovered:

Expand to all the drugs that have ingredients of zolmitriptan:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zomig:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Intervertebral disc protrusion:

Browse all the conditions that are associated with Intervertebral disc protrusion:


How the study uses the data?

The study uses data from the FDA. It is based on zolmitriptan (the active ingredients of Zomig) and Zomig (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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