Zomig and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Zomig (zolmitriptan), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Methylprednisolone, and have Pain.

The phase IV clinical study analyzes which people have Sciatica when taking Zomig. It is created by eHealthMe based on reports of 6,908 people who have side effects when taking Zomig from the FDA, and is updated regularly.

What is Zomig?

Zomig has active ingredients of zolmitriptan. It is often used in migraine. eHealthMe is studying from 7,356 Zomig users. Check the latest studies of Zomig.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,137 drugs and 1,437 conditions by eHealthMe. Check the latest studies of Sciatica.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

6,908 people reported to have side effects when taking Zomig.
Among them, 18 people (0.26%) have Sciatica.

Could Zomig cause Sciatica?

Among these 18 people:

How long have people been on Zomig when they have Sciatica? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Sciatica when taking Zomig? *

  • female: 88.89 %
  • male: 11.11 %

What is the age of people who have Sciatica when taking Zomig? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 23.53 %
  • 40-49: 52.94 %
  • 50-59: 17.65 %
  • 60+: 5.88 %

What are other drugs people take besides Zomig? *

  1. Vicodin: 9 people, 50.00%
  2. Methylprednisolone: 9 people, 50.00%
  3. Amoxicillin: 8 people, 44.44%
  4. Aredia: 8 people, 44.44%
  5. Neurontin: 8 people, 44.44%
  6. Albuterol: 8 people, 44.44%
  7. Zometa: 8 people, 44.44%
  8. Azithromycin: 7 people, 38.89%
  9. Mobic: 7 people, 38.89%
  10. Vioxx: 7 people, 38.89%

What are other side effects people have besides Sciatica? *

  1. Stress And Anxiety: 12 people, 66.67%
  2. Headache (pain in head): 10 people, 55.56%
  3. Pain: 10 people, 55.56%
  4. Fibromyalgia (a long-term condition which causes pain all over the body): 10 people, 55.56%
  5. Dyslipidaemia (abnormal amount of lipids): 9 people, 50.00%
  6. Back Pain: 9 people, 50.00%
  7. Intervertebral Disc Degeneration (spinal disc degeneration): 8 people, 44.44%
  8. Dry Eyes (lack of adequate tears): 8 people, 44.44%
  9. Ear Pain: 8 people, 44.44%
  10. Decreased Interest: 8 people, 44.44%

What are the existing conditions these people have? *

  1. Pain: 4 people, 22.22%
  2. Cervicobrachial Syndrome (pain in neck and arm with changing location): 3 people, 16.67%
  3. Osteoporosis (bones weak and more likely to break): 3 people, 16.67%
  4. Muscle Spasms (muscle contraction): 3 people, 16.67%
  5. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 16.67%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 16.67%
  7. Upper Respiratory Tract Infection: 2 people, 11.11%
  8. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 11.11%
  9. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 11.11%
  10. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Zomig and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zomig:

Sciatica treatments and more:

How severe was Sciatica and when was it recovered:

Expand to all the drugs that have ingredients of zolmitriptan:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zomig:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Browse all the conditions that are associated with Sciatica:


How the study uses the data?

The study uses data from the FDA. It is based on zolmitriptan (the active ingredients of Zomig) and Zomig (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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