Zonegran and Sinus tachycardia - a phase IV clinical study of FDA data

Summary:

Sinus tachycardia is reported as a side effect among people who take Zonegran (zonisamide), especially for people who are female, 30-39 old, have been taking the drug for 1 - 2 years also take Ativan, and have Pain.

The phase IV clinical study analyzes which people have Sinus tachycardia when taking Zonegran. It is created by eHealthMe based on reports of 5,875 people who have side effects when taking Zonegran from the FDA, and is updated regularly.

What is Zonegran?

Zonegran has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 6,211 Zonegran users. Check the latest studies of Zonegran.

What is Sinus tachycardia?

Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node) is found to be associated with 1,268 drugs and 1,412 conditions by eHealthMe. Check the latest studies of Sinus tachycardia.



On Aug, 08, 2026

5,875 people reported to have side effects when taking Zonegran.
Among them, 16 people (0.27%) have Sinus tachycardia.

Could Zonegran cause Sinus tachycardia?

Among these 16 people:

How long have people been on Zonegran when they have Sinus tachycardia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Sinus tachycardia when taking Zonegran? *

  • female: 75 %
  • male: 25 %

What is the age of people who have Sinus tachycardia when taking Zonegran? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 22.22 %
  • 30-39: 55.56 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 22.22 %

What are other drugs people take besides Zonegran? *

  1. Albuterol: 9 people, 56.25%
  2. Ativan: 9 people, 56.25%
  3. Zoloft: 8 people, 50.00%
  4. Benadryl: 8 people, 50.00%
  5. Flexeril: 8 people, 50.00%
  6. Xanax: 8 people, 50.00%
  7. Prilosec: 8 people, 50.00%
  8. Combivent: 7 people, 43.75%
  9. Premarin: 7 people, 43.75%
  10. Buspar: 7 people, 43.75%

What are other side effects people have besides Sinus tachycardia? *

  1. Stress And Anxiety: 10 people, 62.50%
  2. Chest Pain: 10 people, 62.50%
  3. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 56.25%
  4. Depression: 9 people, 56.25%
  5. Oedema Peripheral (superficial swelling): 8 people, 50.00%
  6. Pain In Extremity: 8 people, 50.00%
  7. Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 8 people, 50.00%
  8. Dyspnea (difficult or laboured breathing): 8 people, 50.00%
  9. Joint Pain: 7 people, 43.75%
  10. Drug Dependence: 7 people, 43.75%

What are the existing conditions these people have? *

  1. Pain: 7 people, 43.75%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
  3. Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 6.25%
  4. Breast Cancer: 1 person, 6.25%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Zonegran and have Sinus tachycardia?

- Check whether Sinus tachycardia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zonegran:

Sinus tachycardia treatments and more:

How severe was Sinus tachycardia and when was it recovered:

Expand to all the drugs that have ingredients of zonisamide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zonegran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus tachycardia:

Browse all the conditions that are associated with Sinus tachycardia:


How the study uses the data?

The study uses data from the FDA. It is based on zonisamide (the active ingredients of Zonegran) and Zonegran (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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