Zonisamide and Choroidal effusion - a phase IV clinical study of FDA data

Summary:

Choroidal effusion is reported as a side effect among people who take Zonisamide (zonisamide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Astepro, and have Essential tremor.

The phase IV clinical study analyzes which people have Choroidal effusion when taking Zonisamide. It is created by eHealthMe based on reports of 11,045 people who have side effects when taking Zonisamide from the FDA, and is updated regularly.

What is Zonisamide?

Zonisamide has active ingredients of zonisamide. It is often used in epilepsy. eHealthMe is studying from 11,445 Zonisamide users. Check the latest studies of Zonisamide.

What is Choroidal effusion?

Choroidal effusion (fluid collection in vascular layer of eye that nourishes retina) is found to be associated with 52 drugs and 127 conditions by eHealthMe. Check the latest studies of Choroidal effusion.

On Jul, 17, 2026

11,045 people reported to have side effects when taking Zonisamide.
Among them, 35 people (0.32%) have Choroidal effusion.

Could Zonisamide cause Choroidal effusion?

Among these 35 people:

How long have people been on Zonisamide when they have Choroidal effusion? *

What is the gender of people who have Choroidal effusion when taking Zonisamide? *

female: 48.39 %
male: 51.61 %

What is the age of people who have Choroidal effusion when taking Zonisamide? *

What are other drugs people take besides Zonisamide? *

Imitrex: 6 people, 17.14%
Astepro: 6 people, 17.14%
Qvar: 4 people, 11.43%
Brinzolamide: 1 person, 2.86%
Brimonidine: 1 person, 2.86%

What are other side effects people have besides Choroidal effusion? *

Angle Closure Glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity): 14 people, 40.00%
Vision Blurred: 6 people, 17.14%
Nearsightedness (difficulty in seeing the far objects): 5 people, 14.29%
Choroidal Detachment (separation of vascular layer of the eye): 4 people, 11.43%
Intraocular Pressure Increased: 1 person, 2.86%

What are the existing conditions these people have? *

Essential Tremor: 25 people, 71.43%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 5 people, 14.29%
Glaucoma (increased fluid pressure in the eye with vision loss): 4 people, 11.43%
Sinusitis (inflammation of sinus): 2 people, 5.71%
Recession Of Chamber Angle Of Eye (glaucoma that is due to damage to the anterior chamber of the eye): 2 people, 5.71%
Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Zonisamide and have Choroidal effusion?

- Check whether Choroidal effusion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zonisamide:

Zonisamide (11,445 reports)

Browse all side effects of Zonisamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Choroidal effusion:

Choroidal effusion (52 drugs)

Browse all the conditions that are associated with Choroidal effusion:

Choroidal effusion (127 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on zonisamide (the active ingredients of Zonisamide) and Zonisamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.