Zopiclone and Low density lipoprotein increased - a phase IV clinical study of FDA data

Summary:

Low density lipoprotein increased is reported as a side effect among people who take Zopiclone (eszopiclone), especially for people who are female, 40-49 old, also take Humira, and have Psoriasis.

The phase IV clinical study analyzes which people have Low density lipoprotein increased when taking Zopiclone. It is created by eHealthMe based on reports of 52,551 people who have side effects when taking Zopiclone from the FDA, and is updated regularly.

What is Zopiclone?

Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,331 Zopiclone users. Check the latest studies of Zopiclone.

What is Low density lipoprotein increased?

Low density lipoprotein increased (cholesterol increased in blood) is found to be associated with 745 drugs and 771 conditions by eHealthMe. Check the latest studies of Low density lipoprotein increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

52,551 people reported to have side effects when taking Zopiclone.
Among them, 25 people (0.05%) have Low density lipoprotein increased.

Could Zopiclone cause Low density lipoprotein increased?

Among these 25 people:

What is the gender of people who have Low density lipoprotein increased when taking Zopiclone? *

female: 84 %
male: 16 %

What is the age of people who have Low density lipoprotein increased when taking Zopiclone? *

What are other drugs people take besides Zopiclone? *

What are other side effects people have besides Low density lipoprotein increased? *

Joint Pain: 17 people, 68.00%
Haemoglobin Decreased: 14 people, 56.00%
Blood Creatinine Decreased: 13 people, 52.00%
Pain In Extremity: 13 people, 52.00%
Glycosylated Haemoglobin Increased: 13 people, 52.00%
Red Blood Cell Sedimentation Rate Increased: 12 people, 48.00%
Joint Swelling: 12 people, 48.00%
Nausea (feeling of having an urge to vomit): 12 people, 48.00%
Joint Effusion (presence of extra fluid in joint covering): 12 people, 48.00%
Inflammatory Marker Increased: 12 people, 48.00%

What are the existing conditions these people have? *

Psoriasis (immune-mediated disease that affects the skin): 12 people, 48.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 11 people, 44.00%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 24.00%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 12.00%
Hidradenitis (chronic disease of a type of sweat gland): 2 people, 8.00%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 4.00%
Birth Control: 1 person, 4.00%
Alcoholism (problems with alcohol): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Zopiclone and have Low density lipoprotein increased?

- Check whether Low density lipoprotein increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zopiclone:

Zopiclone (54,331 reports)

Browse all side effects of Zopiclone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Low density lipoprotein increased:

Low density lipoprotein increased (745 drugs)

Browse all the conditions that are associated with Low density lipoprotein increased:

Low density lipoprotein increased (771 conditions)

Related publications that referenced our studies

Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on eszopiclone (the active ingredients of Zopiclone) and Zopiclone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.