Zopiclone and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Zopiclone (eszopiclone), especially for people who are female, 50-59 old, also take Actemra, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Zopiclone. It is created by eHealthMe based on reports of 52,551 people who have side effects when taking Zopiclone from the FDA, and is updated regularly.

What is Zopiclone?

Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,327 Zopiclone users. Check the latest studies of Zopiclone.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,705 drugs and 1,582 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On Sep, 05, 2025

52,551 people reported to have side effects when taking Zopiclone.
Among them, 67 people (0.13%) have Thyroid function test abnormal.

Could Zopiclone cause Thyroid function test abnormal?

Among these 67 people:

What is the gender of people who have Thyroid function test abnormal when taking Zopiclone? *

female: 88.52 %
male: 11.48 %

What is the age of people who have Thyroid function test abnormal when taking Zopiclone? *

What are other drugs people take besides Zopiclone? *

What are other side effects people have besides Thyroid function test abnormal? *

Fatigue (feeling of tiredness): 43 people, 64.18%
Nausea (feeling of having an urge to vomit): 38 people, 56.72%
Malaise (a feeling of general discomfort or uneasiness): 34 people, 50.75%
Rashes (redness): 31 people, 46.27%
Nasopharyngitis (inflammation of the nasopharynx): 29 people, 43.28%
Confusional State: 28 people, 41.79%
Pain: 28 people, 41.79%
Abdominal Pain Upper: 27 people, 40.30%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 26 people, 38.81%
Dyspnea (difficult or laboured breathing): 24 people, 35.82%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 30 people, 44.78%
Pain: 24 people, 35.82%
Urinary Tract Infection: 17 people, 25.37%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 12 people, 17.91%
Malignant Melanoma (skin cancer rises from melancytes): 5 people, 7.46%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 7.46%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 4.48%
Constipation: 3 people, 4.48%
Sciatic Nerve Injury: 3 people, 4.48%
Headache (pain in head): 3 people, 4.48%

* Approximation only. Some reports may have incomplete information.

Do you take Zopiclone and have Thyroid function test abnormal?

- Check whether Thyroid function test abnormal is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zopiclone:

Zopiclone (54,327 reports)

Browse all side effects of Zopiclone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,705 drugs)

Browse all the conditions that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,582 conditions)

Drugs similar to Zopiclone and Thyroid function test abnormal :

Related publications that referenced our studies

Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on eszopiclone (the active ingredients of Zopiclone) and Zopiclone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.