Zosyn and Oedema peripheral - a phase IV clinical study of FDA data

Summary:

Oedema peripheral is reported as a side effect among people who take Zosyn (piperacillin sodium; tazobactam sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Oedema peripheral when taking Zosyn. It is created by eHealthMe based on reports of 10,175 people who have side effects when taking Zosyn from the FDA, and is updated regularly.

What is Zosyn?

Zosyn has active ingredients of piperacillin sodium; tazobactam sodium. It is often used in pneumonia. eHealthMe is studying from 10,236 Zosyn users. Check the latest studies of Zosyn.

What is Oedema peripheral?

Oedema peripheral (superficial swelling) is found to be associated with 2,774 drugs and 3,465 conditions by eHealthMe. Check the latest studies of Oedema peripheral.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

10,175 people reported to have side effects when taking Zosyn.
Among them, 290 people (2.85%) have Oedema peripheral.

Among these 290 people:

* Approximation only. Some reports may have incomplete information.

Do you take Zosyn and have Oedema peripheral?

- Check whether Oedema peripheral is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zosyn:

Zosyn (10,236 reports)

Oedema peripheral treatments and more:

Oedema peripheral (172,690 reports)

How severe was Oedema peripheral and when was it recovered:

Oedema peripheral in Zosyn

Expand to all the drugs that have ingredients of piperacillin sodium; tazobactam sodium:

Oedema peripheral and drugs with ingredients of piperacillin sodium; tazobactam sodium (558 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zosyn:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Oedema peripheral:

Oedema peripheral (2,774 drugs)

Browse all the conditions that are associated with Oedema peripheral:

Oedema peripheral (3,465 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on piperacillin sodium; tazobactam sodium (the active ingredients of Zosyn) and Zosyn (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.