Zyflo cr and Asthma aggravated - a phase IV clinical study of FDA data

Summary:

Asthma aggravated is reported as a side effect among people who take Zyflo cr (zileuton), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Xolair, and have Laryngospasm.

The phase IV clinical study analyzes which people have Asthma aggravated when taking Zyflo cr. It is created by eHealthMe based on reports of 169 people who have side effects when taking Zyflo cr from the FDA, and is updated regularly.

What is Zyflo cr?

Zyflo cr has active ingredients of zileuton. It is often used in asthma. eHealthMe is studying from 184 Zyflo cr users. Check the latest studies of Zyflo cr.

What is Asthma aggravated?

Asthma aggravated is found to be associated with 1,804 drugs and 637 conditions by eHealthMe. Check the latest studies of Asthma aggravated.



On Jul, 13, 2026

169 people reported to have side effects when taking Zyflo cr.
Among them, 13 people (7.69%) have Asthma aggravated.

Could Zyflo cr cause Asthma aggravated?

Among these 13 people:

How long have people been on Zyflo cr when they have Asthma aggravated? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Asthma aggravated when taking Zyflo cr? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Asthma aggravated when taking Zyflo cr? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 14.29 %
  • 20-29: 0.0 %
  • 30-39: 14.29 %
  • 40-49: 28.57 %
  • 50-59: 14.29 %
  • 60+: 28.57 %

What are other drugs people take besides Zyflo cr? *

  1. Xolair: 8 people, 61.54%
  2. Singulair: 6 people, 46.15%
  3. Zyrtec: 4 people, 30.77%
  4. Dexilant: 3 people, 23.08%
  5. Tamiflu: 3 people, 23.08%
  6. Albuterol: 3 people, 23.08%
  7. Klor-Con M20: 2 people, 15.38%
  8. Levaquin: 2 people, 15.38%
  9. Combivent: 2 people, 15.38%
  10. Mucinex D: 2 people, 15.38%

What are other side effects people have besides Asthma aggravated? *

  1. Fatigue (feeling of tiredness): 5 people, 38.46%
  2. Itching: 4 people, 30.77%
  3. Malaise (a feeling of general discomfort or uneasiness): 3 people, 23.08%
  4. Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 23.08%
  5. Throat Irritation: 3 people, 23.08%
  6. Rhinorrhea (watery mucus discharge from the nose): 3 people, 23.08%
  7. Conjunctivitis Allergic (inflammation of the conjunctiva due to allergy): 3 people, 23.08%
  8. Cough: 3 people, 23.08%
  9. Dyspnea (difficult or laboured breathing): 3 people, 23.08%
  10. Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx): 2 people, 15.38%

What are the existing conditions these people have? *

  1. Seasonal Allergy (allergic condition due to certain season): 1 person, 7.69%
  2. Osteopenia (a condition where bone mineral density is lower than normal): 1 person, 7.69%
  3. Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Zyflo cr and have Asthma aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyflo cr:

Asthma aggravated treatments and more:

How severe was Asthma aggravated and when was it recovered:

Expand to all the drugs that have ingredients of zileuton:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zyflo cr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Asthma aggravated:

Browse all the conditions that are associated with Asthma aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on zileuton (the active ingredients of Zyflo cr) and Zyflo cr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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