Zykadia and Metastasis - a phase IV clinical study of FDA data

Summary:

Metastasis is reported as a side effect among people who take Zykadia (ceritinib), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Xalkori, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Metastasis when taking Zykadia. It is created by eHealthMe based on reports of 2,091 people who have side effects when taking Zykadia from the FDA, and is updated regularly.

What is Zykadia?

Zykadia has active ingredients of ceritinib. eHealthMe is studying from 2,091 Zykadia users. Check the latest studies of Zykadia.

What is Metastasis?

Metastasis (spreadable cancer to other organ from origin) is found to be associated with 528 drugs and 842 conditions by eHealthMe. Check the latest studies of Metastasis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

2,091 people reported to have side effects when taking Zykadia.
Among them, 14 people (0.67%) have Metastasis.

Among these 14 people:

How long have people been on Zykadia when they have Metastasis? *

What is the gender of people who have Metastasis when taking Zykadia? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Metastasis when taking Zykadia? *

What are other drugs people take besides Zykadia? *

Xalkori: 1 person, 7.14%

What are other side effects people have besides Metastasis? *

Malignant Neoplasm Progression (cancer tumour came back): 7 people, 50.00%
Metastases To Central Nervous System (cancer spreads to central nervous system): 4 people, 28.57%
Nausea (feeling of having an urge to vomit): 4 people, 28.57%
Diarrhea: 4 people, 28.57%
Dry Skin: 3 people, 21.43%
Generalised Oedema (swelling all over the body): 3 people, 21.43%
Urinary Retention (the inability to completely or partially empty the bladder): 3 people, 21.43%
Ureteric Stenosis (abnormal narrowing or contraction of a duct or canal): 3 people, 21.43%
Haemorrhage (bleeding): 3 people, 21.43%
Seborrheic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 3 people, 21.43%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 11 people, 78.57%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 14.29%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 7.14%
Malignant Neoplasm Progression (cancer tumour came back): 1 person, 7.14%
Lung Adenocarcinoma Metastatic (a form of non-small cell lung cancer spreads to other part): 1 person, 7.14%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Zykadia and have Metastasis?

- Check whether Metastasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zykadia:

Zykadia (2,091 reports)

Metastasis treatments and more:

Metastasis (11,222 reports)

Browse all side effects of Zykadia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Metastasis:

Metastasis (528 drugs)

Browse all the conditions that are associated with Metastasis:

Metastasis (842 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ceritinib (the active ingredients of Zykadia) and Zykadia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.