Zyprexa zydis and Muscle rigidity - a phase IV clinical study of FDA data

Summary:

Muscle rigidity is reported as a side effect among people who take Zyprexa zydis (olanzapine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zyprexa, and have Acute psychosis.

The phase IV clinical study analyzes which people have Muscle rigidity when taking Zyprexa zydis. It is created by eHealthMe based on reports of 1,280 people who have side effects when taking Zyprexa zydis from the FDA, and is updated regularly.

What is Zyprexa zydis?

Zyprexa zydis has active ingredients of olanzapine. It is often used in stress and anxiety. eHealthMe is studying from 1,327 Zyprexa zydis users. Check the latest studies of Zyprexa zydis.

What is Muscle rigidity?

Muscle rigidity (muscle stiffness) is found to be associated with 787 drugs and 1,035 conditions by eHealthMe. Check the latest studies of Muscle rigidity.

On Jul, 04, 2026

1,280 people reported to have side effects when taking Zyprexa zydis.
Among them, 18 people (1.41%) have Muscle rigidity.

Could Zyprexa zydis cause Muscle rigidity?

Among these 18 people:

How long have people been on Zyprexa zydis when they have Muscle rigidity? *

What is the gender of people who have Muscle rigidity when taking Zyprexa zydis? *

female: 61.11 %
male: 38.89 %

What is the age of people who have Muscle rigidity when taking Zyprexa zydis? *

What are other drugs people take besides Zyprexa zydis? *

What are other side effects people have besides Muscle rigidity? *

Confusional State: 8 people, 44.44%
Road Traffic Accident: 7 people, 38.89%
Tremor (trembling or shaking movements in one or more parts of your body): 6 people, 33.33%
Speech Impairment (Adult) (inability to speak (adult)): 6 people, 33.33%
Oral Pain: 5 people, 27.78%
Dizziness: 5 people, 27.78%
Occult Blood Positive: 5 people, 27.78%
Nuchal Rigidity (a resistance to flexion of the neck): 5 people, 27.78%
Crepitations (noises are produced by the rubbing of parts one against the other): 5 people, 27.78%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 5 people, 27.78%

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 11.11%
Acute Psychosis (period of mentally unstable behaviour): 2 people, 11.11%
Psychotic Disorder: 1 person, 5.56%
Nausea (feeling of having an urge to vomit): 1 person, 5.56%
Hypersensitivity: 1 person, 5.56%
High Blood Pressure: 1 person, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.56%
Diabetes: 1 person, 5.56%
Depressive Symptom: 1 person, 5.56%
Constipation: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Zyprexa zydis and have Muscle rigidity?

- Check whether Muscle rigidity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyprexa zydis:

Zyprexa zydis (1,327 reports)

Muscle rigidity treatments and more:

Muscle rigidity (16,888 reports)

Browse all side effects of Zyprexa zydis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle rigidity:

Muscle rigidity (787 drugs)

Browse all the conditions that are associated with Muscle rigidity:

Muscle rigidity (1,035 conditions)

Related publications that referenced our studies

Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on olanzapine (the active ingredients of Zyprexa zydis) and Zyprexa zydis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.