Zyprexa and Rectal fissure - a phase IV clinical study of FDA data

Summary:

Rectal fissure is reported as a side effect among people who take Zyprexa (olanzapine), especially for people who are male, 20-29 old, also take Asacol, and have Crohn's disease.

The phase IV clinical study analyzes which people have Rectal fissure when taking Zyprexa. It is created by eHealthMe based on reports of 63,412 people who have side effects when taking Zyprexa from the FDA, and is updated regularly.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.

What is Rectal fissure?

Rectal fissure (painful condition in which a cut or tear occurs in the anus) is found to be associated with 217 drugs and 298 conditions by eHealthMe. Check the latest studies of Rectal fissure.

On Jul, 04, 2026

63,412 people reported to have side effects when taking Zyprexa.
Among them, 21 people (0.03%) have Rectal fissure.

Among these 21 people:

What is the gender of people who have Rectal fissure when taking Zyprexa? *

female: 40 %
male: 60 %

What is the age of people who have Rectal fissure when taking Zyprexa? *

What are other drugs people take besides Zyprexa? *

What are other side effects people have besides Rectal fissure? *

Anorectal Abscess: 17 people, 80.95%
Stable Angina (a constant chest pain): 16 people, 76.19%
Oropharyngeal Pain: 16 people, 76.19%
Drug Level Decreased: 16 people, 76.19%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 16 people, 76.19%
Fatigue (feeling of tiredness): 16 people, 76.19%
The Flu (the flu is caused by an influenza virus): 15 people, 71.43%
Cough: 15 people, 71.43%
Fistula (an abnormal connection or passageway between two): 13 people, 61.90%
Rhinorrhea (watery mucus discharge from the nose): 13 people, 61.90%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 16 people, 76.19%
Breast Cancer: 4 people, 19.05%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 4.76%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 4.76%
Insomnia (sleeplessness): 1 person, 4.76%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 4.76%
Acne Cystic (skin problems that cause pimples): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Zyprexa and have Rectal fissure?

- Check whether Rectal fissure is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zyprexa:

Zyprexa (64,724 reports)

Rectal fissure treatments and more:

Rectal fissure (1,022 reports)

Browse all side effects of Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Rectal fissure:

Rectal fissure (217 drugs)

Browse all the conditions that are associated with Rectal fissure:

Rectal fissure (298 conditions)

Related publications that referenced our studies

Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on olanzapine (the active ingredients of Zyprexa) and Zyprexa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.